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8450 CUL4B

8450

CUL4B

cullin 4B

protein-coding

Homo sapiens

基因描述

Type Description
Definition cullin 4B

研究结论

Date Results Publications
2021-03-06 13:32:00 CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy. 32466489
2021-01-02 12:49:00 Alu-mediated Xq24 deletion encompassing CUL4B, LAMP2, ATP1B4, TMEM255A, and ZBTB33 genes causes Danon disease in a female patient. 31729179
2020-09-05 13:55:00 NCBP1 promotes the development of lung adenocarcinoma through up-regulation of CUL4B. 31448526
2020-08-12 12:10:00 An autophagy-related (ATG) protein that plays a critical role in autophagosome biogenesis, is a direct substrate of CUL4-RING ubiquitin ligases (CRL4s). 30898011
2020-06-13 12:23:00 Results demonstrate a key contribution of CUL4B overexpression in the malignant behavior of head and neck squamous cell carcinoma (HNSCC) cells, at least in part through the stimulation of angiogenesis and the activation of the Wnt/beta-catenin signaling pathway. 30883036

名称对应

Type IDs
Synonymous CUL-4B, MRXHF2, MRXS15, MRXSC, SFM2
Gene
UniProtKB-ID: CUL4B_HUMAN, K4DI93_HUMAN
UniprotKB: Q13620, K4DI93
UniParc: UPI0000246E48, UPI00001286A6, UPI000024704E, UPI000059DB7F
EMBL: CH471107, BC036216, AL451005, AK123688, AF212995, AC002476, AB014595, U58091, BX537787, AK315037, AY365125, AK299081
Ensembl: ENSG00000158290
KO: hsa:8450
Nucleutide sequences
EMBL-CDS: BAA31670.2, BAG53936.1, AAK16812.1, BAG37520.1, CAD97843.1, AAB67315.1, AAH36216.1, EAX11877.1, AAC50548.1, BAH12944.1, AAR13073.1, EAX11880.1
Gene_ORFName: hCG_40765
Ensembl_TRS: ENST00000371323, ENST00000371322, ENST00000404115, ENST00000336592
Protein sequencees
Ensembl_PRO: ENSP00000384109, ENSP00000360374, ENSP00000360373, ENSP00000338919
RefSeq: NP_001317553.1, NP_003579.3, NP_001356074.1, NP_001073341.1
Others
UniRef100: UniRef100_Q13620, UniRef100_K4DI93
UniRef90: UniRef90_Q13620
UniRef50: UniRef50_Q13620
UniGene: Hs.102914
CCDS: CCDS43987.1, CCDS35379.1

全选

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