| Type | Description |
|---|---|
| Definition | multiple EGF like domains 10 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-12 11:19:00 | Findings indicate that the risk alleles and haplotype near the multiple epidermal growth factor-like-domains 10 (MEGF10) transcription start site (TSS) might modulate transcriptional activity and increase the susceptibility to autism. | 28536440 |
| 2018-10-27 10:45:00 | Results suggested that methylation level and mRNA expression of MEGF10 in glioma were not only correlated with IDH mutation but also associated with clinical outcome of patients. | 29887919 |
| 2017-09-16 13:06:00 | Concentrating on hypermethylated genes to identify candidate tumor suppressor loci, the study found the cell engulfment and adhesion factor gene MEGF10 to be epigenetically repressed by DNA hypermethylation or by H3K27/K9 methylation in neuroblastoma cell lines. | 27862318 |
| 2017-07-29 10:10:00 | MEGF10 mutations can cause myopathy with adult-onset respiratory insufficiency | 26802438 |
| 2014-11-08 11:15:00 | results indicate that myogenin is a positive regulator in transcriptional regulation of MEGF10 in skeletal muscle | 25044114 |
| Type | IDs |
|---|---|
| Synonymous | EMARDD |
| Gene |
UniProtKB-ID:
MEG10_HUMAN
UniprotKB:
Q96KG7
UniParc:
UPI0000070E05,
UPI000006F868
EMBL:
CH471062,
CR749437,
BC020198,
BC152478,
AB058676
Ensembl:
ENSG00000145794
KO:
hsa:84466
|
| Nucleutide sequences |
EMBL-CDS:
EAW62406.1,
BAB47409.2,
AAH20198.1,
CAH18275.1,
AAI52479.1
Ensembl_TRS:
ENST00000274473,
ENST00000418761,
ENST00000503335,
ENST00000508365
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000416284,
ENSP00000274473,
ENSP00000423195,
ENSP00000423354
RefSeq:
NP_001243474.1,
NP_001295050.1,
NP_115822.1,
XP_016865477.1,
NP_001295048.1,
XP_011541996.1,
XP_016865476.1
|
| Others |
UniRef100:
UniRef100_Q96KG7
UniRef90:
UniRef90_Q96KG7
UniRef50:
UniRef50_Q96KG7
UniGene:
Hs.438709
CCDS:
CCDS4142.1,
CCDS78055.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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