| Type | Description |
|---|---|
| Definition | ligand dependent nuclear receptor corepressor |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:10:00 | A decrease of nuclear LCoR expression in line with an increase of dedifferentiation of CIN can be observed. Nuclear LCoR overexpression correlates with CIN II progression indicating a prognostic value of LCoR in cervical intraepithelial neoplasia | 32157438 |
| 2020-04-18 11:07:00 | C10ORF12 protein functions as a positive regulator of PRC2 and facilitates PRC2-mediated H3K27me3 modification of chromatin. | 31186533 |
| 2017-10-14 11:18:00 | Taken together, these results provide new insights into the mechanism of action of LCoR and RIP140 and highlight their strong interplay for the control of gene expression and cell proliferation in breast cancer cells. | 28414308 |
| 2017-09-09 13:01:00 | miR-199a promotes stem cell properties in mammary stem cells and breast cancer stem cells by directly repressing nuclear receptor corepressor LCOR, which primes interferon responses. | 28530657 |
| 2012-06-16 11:27:00 | LCoR recruitment by KLF6 regulates expression of the cyclin-dependent kinase inhibitor CDKN1A gene. | 22277651 |
| Type | IDs |
|---|---|
| Synonymous | C10orf12, MLR2 |
| Gene |
UniProtKB-ID:
LCOR_HUMAN
UniprotKB:
Q96JN0
UniParc:
UPI00001A3E8D,
UPI0000160218,
UPI00001F948C
EMBL:
AL834245,
BC024315,
AL832044,
AL442123,
AL049938,
CH471066,
AK023084,
AB058698,
BC053359,
AL832106
Ensembl:
ENSG00000196233
KO:
hsa:84458
|
| Nucleutide sequences |
EMBL-CDS:
CAD91159.1,
BAB14396.1,
CAB43214.1,
AAH24315.1,
EAW49963.1,
CAD38921.2,
EAW49965.1,
EAW49966.1,
BAB47424.1,
CAD91160.1,
AAH53359.1
Ensembl_TRS:
ENST00000371097,
ENST00000421806,
ENST00000356016,
ENST00000371103,
ENST00000540664
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000443431,
ENSP00000360138,
ENSP00000360144,
ENSP00000348298,
ENSP00000490116
RefSeq:
NP_001164237.1,
NP_001164236.1,
NP_001333445.1,
NP_115816.2
|
| Others |
UniRef100:
UniRef100_Q96JN0
UniRef90:
UniRef90_Q96JN0
UniRef50:
UniRef50_Q96JN0
UniGene:
Hs.745068
CCDS:
CCDS86132.1,
CCDS7451.1,
CCDS53561.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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