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84447 SYVN1

84447

SYVN1

synoviolin 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition synoviolin 1

研究结论

Date Results Publications
2021-02-06 13:53:00 Sel1L-Hrd1 ER-associated degradation maintains beta cell identity via TGF-beta signaling. 32182217
2020-08-01 14:39:00 The authors propose a mechanism of lung tumorigenesis that involves HRD1-mediated downregulation of SIRT2 and suggest that interventions targeting HRD1 activity could be a potential therapeutic strategy to treat patients with lung cancer. 31932479
2020-01-25 14:20:00 This structural analysis unveiled the position and range of the active site of HRD1_RING that contribute to its specific ubiquitin-conjugating enzyme (E2)-binding capability. 30345569
2019-10-12 12:56:00 association of the degradation factor HRD1 with the translocon and the rerouting factor Derlin-1 may be necessary for the smooth and effective clearance of ERpQC substrates 29743537
2019-09-21 11:38:00 A negative correlation between HRD1 and PTEN expression. 29958993

名称对应

Type IDs
Synonymous DER3, HRD1
Gene
UniProtKB-ID: SYVN1_HUMAN
UniprotKB: Q86TM6
UniParc: UPI000004EE90, UPI000006CFBD, UPI00005A610A
EMBL: BC030530, AB058713, AF317634, AL834262, AB024690, AB085847
Ensembl: ENSG00000162298
KO: hsa:84447
Nucleutide sequences
EMBL-CDS: CAD38937.1, AAH30530.1, BAC57449.1, AAL26903.1, BAB47439.1, BAC24801.1
Ensembl_TRS: ENST00000307289, ENST00000294256, ENST00000377190, ENST00000526060
Protein sequencees
Ensembl_PRO: ENSP00000366395, ENSP00000294256, ENSP00000302035, ENSP00000436984
RefSeq: NP_115807.1, XP_011543605.1, NP_757385.1
Others
UniRef100: UniRef100_Q86TM6
UniRef90: UniRef90_Q86TM6
UniRef50: UniRef50_Q86TM6
UniGene: Hs.75859
CCDS: CCDS8097.1, CCDS31605.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

Institute of Medical Science

7
2

Stanford University

5
3

University of Michigan Medical School

5
4

Howard Hughes Medical Institute

4
5

University Medical Center Utrecht

4
热点人员
排名 研究人员 文献
1

Toshihiro Nakajima

11
2

Masayuki Kaneko

11
3

Naoko Yagishita

9
4

Yihong Ye

8
5

Kusuki Nishioka

8
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