| Type | Description |
|---|---|
| Definition | synoviolin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:53:00 | Sel1L-Hrd1 ER-associated degradation maintains beta cell identity via TGF-beta signaling. | 32182217 |
| 2020-08-01 14:39:00 | The authors propose a mechanism of lung tumorigenesis that involves HRD1-mediated downregulation of SIRT2 and suggest that interventions targeting HRD1 activity could be a potential therapeutic strategy to treat patients with lung cancer. | 31932479 |
| 2020-01-25 14:20:00 | This structural analysis unveiled the position and range of the active site of HRD1_RING that contribute to its specific ubiquitin-conjugating enzyme (E2)-binding capability. | 30345569 |
| 2019-10-12 12:56:00 | association of the degradation factor HRD1 with the translocon and the rerouting factor Derlin-1 may be necessary for the smooth and effective clearance of ERpQC substrates | 29743537 |
| 2019-09-21 11:38:00 | A negative correlation between HRD1 and PTEN expression. | 29958993 |
| Type | IDs |
|---|---|
| Synonymous | DER3, HRD1 |
| Gene |
UniProtKB-ID:
SYVN1_HUMAN
UniprotKB:
Q86TM6
UniParc:
UPI000004EE90,
UPI000006CFBD,
UPI00005A610A
EMBL:
BC030530,
AB058713,
AF317634,
AL834262,
AB024690,
AB085847
Ensembl:
ENSG00000162298
KO:
hsa:84447
|
| Nucleutide sequences |
EMBL-CDS:
CAD38937.1,
AAH30530.1,
BAC57449.1,
AAL26903.1,
BAB47439.1,
BAC24801.1
Ensembl_TRS:
ENST00000307289,
ENST00000294256,
ENST00000377190,
ENST00000526060
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366395,
ENSP00000294256,
ENSP00000302035,
ENSP00000436984
RefSeq:
NP_115807.1,
XP_011543605.1,
NP_757385.1
|
| Others |
UniRef100:
UniRef100_Q86TM6
UniRef90:
UniRef90_Q86TM6
UniRef50:
UniRef50_Q86TM6
UniGene:
Hs.75859
CCDS:
CCDS8097.1,
CCDS31605.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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