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8443 GNPAT

8443

GNPAT

glyceronephosphate O-acyltransferase

protein-coding

Homo sapiens

基因描述

Type Description
Definition glyceronephosphate O-acyltransferase

研究结论

Date Results Publications
2021-01-16 15:59:00 Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis. 31974474
2019-10-12 12:34:00 GNPAT and USP30-mediated stabilization of DRP1 play a critical role in the development of hepatocellular carcinoma 30143522
2018-01-13 10:51:00 GNPAT p.D519G is strongly associated with markedly increased iron stores in p.C282Y homozygotes after correction for age, iron-related variables, and alcohol consumption. 27936396
2017-10-28 12:12:00 GNPAT rs11558492 is not a major modifier of iron status and is not associated with liver fibrosis in HFE-related Hemochromatosis patients. 28425416
2017-05-27 10:26:00 Here, we report the characterization of the recombinant human DHAP acyl-transferase, which performs the first step in alkyl-DHAP synthesis. 27836547

名称对应

Type IDs
Synonymous DAP-AT, DAPAT, DHAPAT, RCDP2
Gene
UniProtKB-ID: GNPAT_HUMAN
UniprotKB: O15228
UniParc: UPI00017A791F, UPI0000000A2A
EMBL: AF218231, AL117352, AF218225, AF218228, AJ002190, AF218224, AF218223, AK297982, AF218233, AF218226, AF043937, AF218232, BC000450, AF218229, AF218227, AF218230, AL137801
Ensembl: ENSG00000116906
KO: hsa:8443
Nucleutide sequences
EMBL-CDS: CAA05242.1, AAG17547.1, AAH00450.1, AAC24505.1, BAG60291.1
Ensembl_TRS: ENST00000366647
Protein sequencees
Ensembl_PRO: ENSP00000355607
RefSeq: XP_011542605.1, XP_011542606.1, NP_001303279.1, NP_055051.1, XP_005273370.1
Others
UniRef100: UniRef100_O15228
UniRef90: UniRef90_O15228
UniRef50: UniRef50_O15228
UniGene: Hs.498028
CCDS: CCDS1592.1

全选

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