| Type | Description |
|---|---|
| Definition | Wnt family member 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 12:16:00 | Study of cisplatin-induced acute kidney injury (AKI) model in rats and clinical study of contrast agent induced AKI is the first to demonstrate that increased expression of renal and urinary Wnt4 can be detected earlier than serum creatinine after drug-induced AKI suggesting that urinary Wnt4 can potentially serve as a noninvasive biomarker for monitoring patients with tubular injury. | 30002385 |
| 2018-08-25 10:51:00 | Compared with the saline Hepatocellular carcinoma (HCC)-group, transplantation with CD34+ human hematopoietic stem cells produced a further increase in the levels of wnt4 (+19.4%) and p53 gene expression (+53%), a 2-fold increase in the percentage of cancer progenitor cells and increased HCC pathology grading | 29429512 |
| 2018-08-18 11:11:00 | This suggests that soybean isoflavones could delay the process of renal interstitial fibrosis in DN rats by decreasing the expression of Wnt4, beta-catenin and TGF-beta1 in the renal interstitium, thus demonstrating that soybean isoflavones plus losartan have the best protective effects against diabetes-induced renal fibrosis. | 29921370 |
| 2015-10-31 10:19:00 | Dvl-1 was probably a key regulator in the pathway of wnt4/beta-catenin to take part in the vascular restenosis in a rat model of balloon-injured carotid artery | 25674206 |
| 2015-02-28 13:08:00 | The 5'-flanking region of the Wnt4 gene is responsive to Pax8. Pax8 modulates the expression of Wnt4 in thyroid cells. | 25270402 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
WNT4_RAT
UniprotKB:
Q9QXQ5
UniParc:
UPI0000138F67
EMBL:
AF188608
KO:
rno:84426
|
| Nucleutide sequences |
EMBL-CDS:
AAF15589.1
|
| Protein sequencees |
RefSeq:
NP_445854.1
|
| Others |
UniRef100:
UniRef100_Q9QXQ5
UniRef90:
UniRef90_P22724
UniRef50:
UniRef50_P22724
UniGene:
Rn.34782
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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