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8440 NCK2

8440

NCK2

NCK adaptor protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition NCK adaptor protein 2

研究结论

Date Results Publications
2020-09-26 13:04:00 Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion. 31638742
2020-07-18 11:04:00 The minor allele frequency (MAF) of rs678350 was significantly higher in NTG patients (MAF = 0.32) than in controls (MAF = 0.23) (OR, 1.586; 95% CI, 1.058 to 2.375; P = 0.028). This trend was more significant in the dominant model (OR, 1.908; 95% CI, 1.144 to 3.180; P = 0.015). 31512042
2018-09-01 11:10:00 This study provides evidence of a possible role of NCK2 as biomarker of ovarian cancer progression. 29218693
2018-07-14 10:10:00 There was no difference in the Nck2 mRNA expression between the SLE patients and the healthy subjects. 29911835
2016-11-12 10:42:00 Nck1 and Nck2 Interact with WTIP. Nck1/2 integrates nephrin with the Hippo kinase cascade through association with the adaptor protein WTIP. 27033705

名称对应

Type IDs
Synonymous GRB4, NCKbeta
Gene
UniProtKB-ID: NCK2_HUMAN, A0A0S2Z4M6_HUMAN, E7ERP6_HUMAN
UniprotKB: O43639, A0A0S2Z4M6, E7ERP6
UniParc: UPI000012FE3F, UPI00004432F7
EMBL: CH471127, KF510749, KU178418, AF047487, AF043119, AC010978, AC009505, KU178419, BC000103, BC007195
Ensembl: ENSG00000071051
KO: hsa:8440
Nucleutide sequences
EMBL-CDS: EAX01753.1, AAH00103.1, AAH07195.1, EAX01754.1, AAC80284.1, AAC04831.1, ALQ33876.1, ALQ33877.1
Ensembl_TRS: ENST00000233154, ENST00000393349, ENST00000451463, ENST00000522586
Protein sequencees
Ensembl_PRO: ENSP00000233154, ENSP00000377018, ENSP00000410428, ENSP00000431109
RefSeq: XP_016860593.1, XP_011510294.2, XP_016860594.1, XP_006712860.1, XP_011510293.1, NP_003572.2, XP_016860592.1, NP_001004720.1, NP_001004722.1
Others
UniRef100: UniRef100_E7ERP6, UniRef100_O43639
UniRef90: UniRef90_O43639, UniRef90_E7ERP6
UniRef50: UniRef50_P16333, UniRef50_E7ERP6
UniGene: Hs.529244, Hs.735723
CCDS: CCDS33266.1

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