| Type | Description |
|---|---|
| Definition | hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:27:00 | The impact of hyperpolarization-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium KCNQ/Kv7 channels on primary microglia function. | 32248813 |
| 2020-05-30 11:57:00 | Results confirm the involvement of the HCN1 subunit in the regulation of input resistance and provide direct evidence that a deficiency of HCN1 caused absence epilepsy in rats. | 30408474 |
| 2020-04-25 12:38:00 | These findings suggest that HCN1 channels contribute to motor coordination and muscle strength, and that the muscle weakness of Hcn1-deficient rats results from the involvement not of the peripheral but of the central nervous system. | 31292305 |
| 2017-11-26 01:10:00 | results implicate presynaptic NMDA receptor inhibition followed by reduced activity of presynaptic HCN1 channels, which would result in an increase in glutamate release and postsynaptic glutamate receptor activity, as a mechanism of ketamine action. | 27965425 |
| 2017-09-30 13:38:00 | HCN channels play a critical role in the separation of overlapping movement responses and allow for successful reaching behaviours. These data provide a novel mechanism for the encoding of multiple movement responses within shared networks of motor cortex. This mechanism supports a viewpoint of primary motor cortex as a site of dynamic integration for behavioural output | 27568501 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HCN1_RAT
UniprotKB:
Q9JKB0
UniParc:
UPI000012C354
EMBL:
AF247450
KO:
rno:84390
|
| Nucleutide sequences |
EMBL-CDS:
AAF62173.1
|
| Protein sequencees |
RefSeq:
NP_445827.1
|
| Others |
UniRef100:
UniRef100_Q9JKB0
UniRef90:
UniRef90_O60741
UniRef50:
UniRef50_O60741
UniGene:
Rn.21408
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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