| Type | Description |
|---|---|
| Definition | coiled-coil domain containing 115 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | Genetic screens reveal CCDC115 as a modulator of erythroid iron and heme trafficking. | 32510613 |
| 2019-03-09 12:35:00 | CCDC115 mutation is associated with Congenital disorders of glycosylation causing liver disease. | 29759592 |
| 2018-12-22 10:03:00 | CCDC115 is associated with less aggressive prostate cancer in humans. | 29890952 |
| 2017-05-06 14:47:00 | Vacuolar H+ ATPase (V-ATPase), the key proton pump for endo-lysosomal acidification, and two previously uncharacterised V-ATPase assembly factors, TMEM199 and CCDC115, stabilise HIF1alpha in aerobic conditions. | 28296633 |
| 2016-06-28 11:17:00 | Our study reveals CCDC115 deficiency as a disorder of Golgi homeostasis that can be readily identified via screening for abnormal glycosylation in plasma. | 26833332 |
| Type | IDs |
|---|---|
| Synonymous | CDG2O, ccp1 |
| Gene |
UniProtKB-ID:
CC115_HUMAN,
B8ZZ99_HUMAN,
A1QKJ6_HUMAN
UniprotKB:
Q96NT0,
B8ZZ99,
A1QKJ6
UniParc:
UPI0000D4D0D1,
UPI00017A7112,
UPI000006E81C
EMBL:
AK054693,
BC006429,
CH471263,
AC132479,
AK295922
Ensembl:
ENSG00000136710
KO:
hsa:84317
|
| Nucleutide sequences |
EMBL-CDS:
AAH06429.2,
BAG58709.1,
AAY24075.1,
BAB70794.1,
EAW55611.1,
EAW55610.1,
EAW55612.1
Gene_ORFName:
hCG_39080,
hCG_39080
Ensembl_TRS:
ENST00000259229,
ENST00000651709,
ENST00000409127
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000499101,
ENSP00000259229,
ENSP00000387301
RefSeq:
NP_001308048.2,
NP_001308047.1,
NP_115733.2
|
| Others |
UniRef100:
UniRef100_Q96NT0,
UniRef100_B8ZZ99
UniRef90:
UniRef90_Q96NT0,
UniRef90_B8ZZ99
UniRef50:
UniRef50_Q96NT0,
UniRef50_Q96NT0-2
UniGene:
Hs.104203
CCDS:
CCDS2159.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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