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843 CASP10

843

CASP10

caspase 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition caspase 10

研究结论

Date Results Publications
2020-01-04 10:09:00 caspase-10 suppresses ATP citrate lyase-promoted malignant phenotype. These findings expand the substrate repertoire of caspase-10 and highlight its pivotal role in inhibiting tumorigenesis through metabolic and epigenetic mechanisms. 31534141
2019-06-29 11:32:00 MicroRNA-421 inhibits caspase-10 expression and promotes breast cancer progression 29322788
2018-03-24 12:11:00 case-control study, including 600 hepatocellular carcinoma (HCC) and 600 HBsAg positive controls without HCC, was conducted to assess the relationship between 11 tagging SNPs in CASP8, CASP10 and CFLAR and HBV-related HCC risk .These results suggest that the CASP8 -652 6N ins/del polymorphism may play a protective role in the development, progression, and survival of HBV-related HCC among the Chinese Han population. 28643196
2018-01-20 10:41:00 Caspase-10 is a negative regulator of cell death and a facilitator of gene induction separates the function of cFLIP and caspase-10 in the death-inducing signaling complex. 28445729
2017-12-30 12:02:00 caspase-10 was dispensable for enhancement of cisplatin/LA-12 and TRAIL combination-induced cell death and stimulation of Bid cleavage 29182622

名称对应

Type IDs
Synonymous ALPS2, FLICE2, MCH4
Gene
UniProtKB-ID: CASPA_HUMAN, A0A0S2Z3G5_HUMAN, A0A0S2Z3Z5_HUMAN
UniprotKB: Q92851, A0A0S2Z3G5, A0A0S2Z3Z5
UniParc: UPI0000367D6F, UPI0000074732, UPI0000421EE8, UPI000002ABA4, UPI000004466C, UPI0000425EF9, UPI000013CA28
EMBL: CH471063, EF050529, U60519, BC042844, AB038979, KU177960, AF111344, AY690601, AC007283, AJ487679, AF111345, KU177959, U86214, AJ487678
Ensembl: ENSG00000003400
KO: hsa:843
Nucleutide sequences
EMBL-CDS: AAD28402.1, AAU00989.1, AAC50644.1, AAD28403.1, ABJ53426.1, EAW70248.1, CAD32371.1, AAY24291.1, EAW70249.1, CAD32372.1, BAB32554.1, AAB46730.1, AAH42844.1, BAB32553.1, ALQ33418.1, EAW70250.1, ALQ33417.1
Gene_ORFName: hCG_16984
Ensembl_TRS: ENST00000272879, ENST00000448480, ENST00000374650, ENST00000360132, ENST00000346817, ENST00000286186, ENST00000313728
Protein sequencees
Ensembl_PRO: ENSP00000272879, ENSP00000363781, ENSP00000237865, ENSP00000314599, ENSP00000286186, ENSP00000353250, ENSP00000396835
RefSeq: XP_006712859.1, XP_005246964.1, NP_001293012.1, NP_116756.2, NP_001193471.1, NP_116758.1, NP_001221.2, NP_001193453.1, NP_116759.2, XP_011510292.1
Others
UniRef100: UniRef100_Q92851-4, UniRef100_Q92851, UniRef100_Q92851-2
UniRef90: UniRef90_Q92851-4, UniRef90_Q92851
UniRef50: UniRef50_Q92851-4, UniRef50_Q92851
UniGene: Hs.5353
CCDS: CCDS2340.1, CCDS77506.1, CCDS56159.1, CCDS2338.1, CCDS56160.1, CCDS2339.1

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