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84299 MIEN1

84299

MIEN1

migration and invasion enhancer 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition migration and invasion enhancer 1

研究结论

Date Results Publications
2020-06-20 11:11:00 data identified that the promotion of gastric cancer (GC) growth and metastasis induced by circRNA_100876 interacted with miR-136 and MIEN1, indicating an emerging announcement for uncovering the potential mechanism of GC progression 32305633
2018-02-24 11:18:00 these results suggest the MIEN1 promoter has a short interspersed nuclear Alu element region that is hypermethylated in normal cells leading to repression of the gene; in cancer, the hypomethylation of a part of this repeat, in addition to the binding of USF, results in MIEN1 expression 27589566
2018-01-20 11:48:00 Data show that migration and invasion enhancer 1 (MIEN1) plays an essential role in maintaining the plasticity of the dynamic membrane-associated actin cytoskeleton, which leads to an increase in cell motility, suggesting targeting MIEN1 might represent a promising means to prevent breast tumor metastasis. 27462783
2017-10-21 10:46:00 Down-regulation of C35 decreased the cell viability and migration of breast ductal carcinoma cells. 28859163
2017-03-18 12:55:00 indicate that MIEN1 overexpression may facilitate migration and invasion in breast cancer 28198505

名称对应

Type IDs
Synonymous C17orf37, C35, ORB3, RDX12, XTP4
Gene
UniProtKB-ID: MIEN1_HUMAN, J3KTI2_HUMAN
UniprotKB: Q9BRT3, J3KTI2
UniParc: UPI000268AFBB, UPI0000043728
EMBL: AY508814, AC079199, BC006006, AF490253
Ensembl: ENSG00000141741
KO: hsa:84299
Nucleutide sequences
EMBL-CDS: AAH06006.1, AAR92035.1, AAO85461.1
Ensembl_TRS: ENST00000394231, ENST00000577810
Protein sequencees
Ensembl_PRO: ENSP00000377778, ENSP00000462998
RefSeq: NP_115715.3, NP_001317135.1
Others
UniRef100: UniRef100_Q9BRT3, UniRef100_J3KTI2
UniRef90: UniRef90_J3KTI2, UniRef90_Q9BRT3
UniRef50: UniRef50_Q9BRT3
UniGene: Hs.333526
CCDS: CCDS11344.1

全选

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研究热度

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