| Type | Description |
|---|---|
| Definition | transmembrane protein 175 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:40:00 | Gating and selectivity mechanisms for the lysosomal K(+) channel TMEM175. | 32228865 |
| 2020-05-16 12:31:00 | Data suggest that the TMEM175 p.M393T variant is responsible for the main signal in the chromosome 4p16.3 locus therefore conferring risk for Parkinson disease through its phosphorylation of alpha-synuclein. | 31261387 |
| 2020-05-16 12:13:00 | Coding variants in TMEM175 are likely to be responsible for the association in the TMEM175/GAK/DGKQ locus, which could be mediated by affecting glucosylceramidase activity. | 31658403 |
| 2018-04-14 10:05:00 | TMEM175 deficiency impairs lysosomal and mitochondrial function and increases alpha-synuclein aggregation. | 28193887 |
| 2017-12-30 12:01:00 | structure of TMEM175 represents a novel architecture of a tetrameric cation channel whose ion selectivity mechanism appears to be distinct from that of the classical K(+) channel family | 28723891 |
| Type | IDs |
|---|---|
| Synonymous | hTMEM175 |
| Gene |
UniProtKB-ID:
TM175_HUMAN,
F6UWG6_HUMAN
UniprotKB:
Q9BSA9,
F6UWG6
UniParc:
UPI000006D795,
UPI0000D4AB4A,
UPI000006D921
EMBL:
AL834199,
BC005158,
AC019103,
CH471131
Ensembl:
ENSG00000127419
KO:
hsa:84286
|
| Nucleutide sequences |
EMBL-CDS:
EAW82638.1,
CAD38888.1,
EAW82633.1,
AAH05158.1,
EAW82637.1,
EAW82636.1,
EAW82640.1
Gene_ORFName:
hCG_34455
Ensembl_TRS:
ENST00000622959,
ENST00000264771,
ENST00000515740,
ENST00000508204
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264771,
ENSP00000485461,
ENSP00000427039,
ENSP00000423669
RefSeq:
NP_001284353.1,
XP_024310022.1,
XP_024310020.1,
XP_005272358.1,
NP_001284352.1,
XP_016864192.1,
XP_005272361.1,
XP_024310023.1,
NP_001284355.1,
XP_016864194.1,
NP_115702.1,
NP_001284357.1,
NP_001284356.1,
XP_024310021.1,
NP_001284354.1,
XP_005272360.1,
XP_016864193.1,
XP_016864190.1,
XP_005272364.1
|
| Others |
UniRef100:
UniRef100_Q9BSA9
UniRef90:
UniRef90_Q9BSA9
UniRef50:
UniRef50_Q9BSA9
UniGene:
Hs.478936
CCDS:
CCDS75088.1,
CCDS3341.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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