| Type | Description |
|---|---|
| Definition | ring finger protein 135 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 10:07:00 | Riplet, and not TRIM25, is required endogenously for the ubiquitination of RIG-I. | 31335993 |
| 2020-02-15 11:56:00 | Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity. | 31006531 |
| 2018-12-22 12:17:00 | Together with Riplet, Ube2D3 promotes covalent conjugation of polyubiquitin chains to RIG-I, while Ube2N preferentially facilitates production of unanchored chains. In the presence of these chains, RIG-I induces MAVS aggregation directly on the mitochondria. Data thus reveal two essential mechanisms underlying the activation of RIG-I and MAVS for triggering innate immune signaling in response to viral infection in cells. | 28469175 |
| 2017-07-15 11:29:00 | In-depth analysis of population-differentiated regions indicated that the coding gene, RNF135, represented a trans-regulation hotspot via cis-regulation by the population-specific variants in the region of selective sweep. | 27992444 |
| 2016-12-31 10:46:00 | findings demonstrate the biological effects of RNF135 in glioblastoma cell proliferation, migration and cell cycle, and its role in the progression of glioblastoma may be associated with the ERK signal transduction pathway. | 26856755 |
| Type | IDs |
|---|---|
| Synonymous | L13, MMFD, REUL, Riplet |
| Gene |
UniProtKB-ID:
RN135_HUMAN,
B3KV69_HUMAN
UniprotKB:
Q8IUD6,
B3KV69
UniParc:
UPI000178DFFC,
UPI00001AF795,
UPI0000072456,
UPI0000D4C294
EMBL:
AK122709,
BC126422,
AB470605,
BC126420,
BC082262,
AY598332,
AK122646,
CH471147,
AC138207,
BC005084,
AK312979,
AJ496729
Ensembl:
ENSG00000181481
KO:
hsa:84282
|
| Nucleutide sequences |
EMBL-CDS:
CAD43140.1,
EAW80286.1,
AAH05084.1,
BAG84604.1,
BAG35816.1,
BAG53638.1,
AAT06743.1,
AAI26423.1,
AAI26421.1,
BAG53681.1
Gene_ORFName:
L13
Ensembl_TRS:
ENST00000324689,
ENST00000328381,
ENST00000535306
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000328340,
ENSP00000440470,
ENSP00000323693
RefSeq:
NP_115698.3,
XP_024306768.1,
XP_024306769.1,
XP_016880712.1,
NP_001171921.1,
NP_922921.1
|
| Others |
UniRef100:
UniRef100_Q8IUD6
UniRef90:
UniRef90_Q8IUD6
UniRef50:
UniRef50_Q8IUD6
UniGene:
Hs.29874
CCDS:
CCDS54104.1,
CCDS11263.1,
CCDS11262.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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