| Type | Description |
|---|---|
| Definition | serine/threonine kinase 24 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 11:22:00 | MST3 protein coats lipid droplets in human liver cells. Knockdown of MST3 attenuated lipid accumulation in human hepatocytes by stimulating beta-oxidation and triacylglycerol secretion while inhibiting fatty acid influx and lipid synthesis. MST3 expression was positively correlated with key features of NASH in human liver biopsies. | 31173506 |
| 2019-11-16 10:38:00 | Down-expression of MST3 in colorectal cancer cell lines enhanced their migration and invasion, but overexpression of MST3 could attenuate miR-222 overexpression in the promotion of migration and invasion in colorectal cell lines. | 31034165 |
| 2019-01-05 12:36:00 | Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. | 29557182 |
| 2018-01-06 11:24:00 | High MST3 expression is associated with breast cancer. | 26910843 |
| 2015-02-07 12:12:00 | This study demonistrated that MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development. | 25456499 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-95, MST3, MST3B, STE20, STK3 |
| Gene |
UniProtKB-ID:
STK24_HUMAN,
Q5U0E6_HUMAN,
B4DR80_HUMAN,
Q6P0Y1_HUMAN
UniprotKB:
Q9Y6E0,
Q5U0E6,
B4DR80,
Q6P0Y1
UniParc:
UPI0000236E51,
UPI00017A7ADB,
UPI000000D94D,
UPI000013606E
EMBL:
EU668350,
BC065378,
AF024636,
CH471085,
BC035578,
AL356423,
AF083420,
AL137249,
BT019619,
AK299140
Ensembl:
ENSG00000102572
KO:
hsa:8428
|
| Nucleutide sequences |
EMBL-CDS:
EAX08986.1,
AAH35578.1,
AAB82560.1,
AAD42039.1,
EAX08987.1,
AAV38425.1,
ACF94503.1,
BAG61192.1,
AAH65378.1
Gene_ORFName:
hCG_27759
Ensembl_TRS:
ENST00000539966,
ENST00000376547,
ENST00000397517
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365730,
ENSP00000442539,
ENSP00000380651
RefSeq:
NP_001273578.1,
XP_005254136.1,
XP_016876283.1,
NP_003567.2,
NP_001027467.2,
XP_024305194.1
|
| Others |
UniRef100:
UniRef100_Q6P0Y1,
UniRef100_Q9Y6E0,
UniRef100_Q5U0E6,
UniRef100_B4DR80
UniRef90:
UniRef90_A0A0D9RY58,
UniRef90_A0A337SJH5,
UniRef90_Q9Y6E0
UniRef50:
UniRef50_Q9Y6E0,
UniRef50_B0LT89,
UniRef50_A0A0D9RY58
UniGene:
Hs.508514
CCDS:
CCDS9488.1,
CCDS32001.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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