| Type | Description |
|---|---|
| Definition | alkB homolog 7 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 10:14:00 | Our results uncovered a SNP of ALKBH7, rs7540, which is associated with prostate cancer disease in a statistically significantly manner in two separate cohorts, and maintained in African American men. | 28231280 |
| 2014-12-20 10:47:00 | ALKBH7 possesses the conserved double-stranded beta-helix fold that coordinates a catalytically active iron by a conserved HX(D/E) em leader Xn em leader H motif. | 25122757 |
| 2013-07-27 11:51:00 | novel role for a AlkB homolog, human ALKBH7, in programmed necrosis, presenting a new target for therapeutic intervention in cancer cells that are resistant to apoptotic cell death | 23666923 |
| Type | IDs |
|---|---|
| Synonymous | ABH7, SPATA11, UNQ6002 |
| Gene |
UniProtKB-ID:
ALKB7_HUMAN
UniprotKB:
Q9BT30
UniParc:
UPI0000039ED9
EMBL:
AY427650,
AK311956,
CH471139,
BC004393,
AC011491,
AK223336,
AY358858
Ensembl:
ENSG00000125652
KO:
hsa:84266
|
| Nucleutide sequences |
EMBL-CDS:
BAD97056.1,
AAQ89217.1,
AAH04393.1,
BAG34896.1,
EAW69102.1,
AAR24624.1
Gene_ORFName:
UNQ6002/PRO34564
Ensembl_TRS:
ENST00000245812
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000245812
RefSeq:
XP_016882844.1,
NP_115682.1,
XP_005259715.1
|
| Others |
UniRef100:
UniRef100_Q9BT30
UniRef90:
UniRef90_Q9BT30
UniRef50:
UniRef50_Q16740
UniGene:
Hs.111099
CCDS:
CCDS12163.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28231280 |
ALKBH7 Variant Related to Prostate Cancer Exhibits Altered Substrate Binding. PLoS Comput. Biol. Alice R Walker , Pavel Silvestrov , Tina A Müller , Robert H Podolsky , Gregory Dyson , Robert P Hausinger , Gerardo Andrés Cisneros |
2017-02-01 | - |
| 25122757 |
J Biol Chem Guoqiang Wang , Qingzhong He , Chong Feng , Yang Liu , Zengqin Deng , Xiaoxuan Qi , Wei Wu , Pinchao Mei , Zhongzhou Chen |
2014-10-03 | - |
| 23666923 |
Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis. Genes Dev. Dragony Fu , Jennifer J Jordan , Leona D Samson |
2013-05-15 |
ALKBH7
|
| 21832049 |
J Biol Chem Judit Oláh , Orsolya Vincze , Dezsõ Virók , Dóra Simon , Zsolt Bozsó , Natália Tõkési , István Horváth , Emma Hlavanda , János Kovács , Anna Magyar , Mária Szũcs , Ferenc Orosz , Botond Penke , Judit Ovádi |
2011-09-30 | - |
| 21182205 |
Proteomics Roberta Tarallo , Angela Bamundo , Giovanni Nassa , Ernesto Nola , Ornella Paris , Concetta Ambrosino , Angelo Facchiano , Marc Baumann , Tuula A Nyman , Alessandro Weisz |
2011-01-01 |
ATP9A,
ACTR3,
ACTR2,
G3BP1,
HNRNPR,
SRRM1,
AKAP8,
RBM14,
SYNCRIP,
MYBBP1A,
DDX17,
NOP56,
KHDRBS1,
RUVBL2,
POP1,
HNRNPA0,
SEC61B,
CHD4,
PSIP1,
SUPT16H,
U2AF2,
FTSJ3,
AP2M1,
CLTC,
WDR36,
MYL6B,
BRI3BP,
PARP1,
HNRNPA1L2,
DNAH2,
DBN1,
DDX3X,
DDX5,
DHX9,
DHX15,
DECR1,
DKC1,
DSG1,
PGAM5,
EIF4A1,
EIF4G1,
EMD,
ESR1,
EWSR1,
HNRNPA3,
DHX30,
RRP1B,
FLNA,
FLNB,
RRP12,
FMR1,
U2SURP,
SF3B1,
RPL13A,
SRRM2,
GTPBP4,
FUS,
RPL36,
GAPDH,
RSL1D1,
GNL3,
TBL2,
PABPC1,
PELP1,
RBMX,
GNB1,
GNB2,
GOLGA2,
SFN,
SLC25A5,
GSN,
GNL2,
H2AFX,
ANXA2,
HDAC1,
HDAC2,
HIF1A,
HNRNPA1,
HNRNPA2B1,
HNRNPAB,
HNRNPF,
HNRNPK,
HPCAL1,
HSPA1L,
HSPA8,
NCCRP1,
APOD,
ILF2,
JUP,
ARG1,
RPSA,
LGALS7,
CAPRIN1,
ARSB,
MKI67,
MYO1B,
MYH9,
MYL6,
MYO1C
|
| 19490893 |
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell Ji Luo , Michael J Emanuele , Danan Li , Chad J Creighton , Michael R Schlabach , Thomas F Westbrook , Kwok-Kin Wong , Stephen J Elledge |
2009-05-29 | - |
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 12975309 |
Genome Res. Hilary F Clark , Austin L Gurney , Evangeline Abaya , Kevin Baker , Daryl Baldwin , Jennifer Brush , Jian Chen , Bernard Chow , Clarissa Chui , Craig Crowley , Bridget Currell , Bethanne Deuel , Patrick Dowd , Dan Eaton , Jessica Foster , Christopher Grimaldi , Qimin Gu , Philip E Hass , Sherry Heldens , Arthur Huang , Hok Seon Kim , Laura Klimowski , Yisheng Jin , Stephanie Johnson , James Lee , Lhney Lewis , Dongzhou Liao , Melanie Mark , Edward Robbie , Celina Sanchez , Jill Schoenfeld , Somasekar Seshagiri , Laura Simmons , Jennifer Singh , Victoria Smith , Jeremy Stinson , Alicia Vagts , Richard Vandlen , Colin Watanabe , David Wieand , Kathryn Woods , Ming-Hong Xie , Daniel Yansura , Sothy Yi , Guoying Yu , Jean Yuan , Min Zhang , Zemin Zhang , Audrey Goddard , William I Wood , Paul Godowski , Alane Gray |
2003-10-01 |
Sdhd,
SIGLEC14,
LOC100127951,
LOC100128035,
LOC100128644,
LOC100128816,
LPEQ6126,
QIQN5815,
UNQ6494,
EPWW6493,
LOC100130071,
LOC100130428,
LRRC70,
LOC100130916,
LOC100131131,
CD300LD,
LOC100131541,
LOC100131826,
LOC100131943,
LOC100132099,
LOC100133106,
C17orf99,
INSL5,
PET117,
TOM1,
SH2D3C,
SH2D3A,
LOC100506242,
CASP12,
HCG8,
LOC100507646,
LOC100508226,
FAM24B-CUZD1,
GPC6,
PINK1-AS,
PPIF,
CDH16,
CLEC3A,
DHRS9,
CNIH1,
MPZL2,
ANGPTL7,
LRRC17,
FSTL3,
CWC27,
CNPY2,
B3GNT3,
CCL26,
PRG3,
SPON2,
LRRN2,
GPNMB,
SEMA6B,
SEMA4B,
FBLN5,
LOC105377021,
AGR2,
OLFM4,
COLEC10,
LEFTY1,
TNFSF13B,
CNPY3,
YME1L1,
ARID5A,
HCST,
LYVE1,
DHRS4,
UTS2,
BTNL3,
PRSS21,
SLC27A3,
KLK11,
ADAM30,
ADAMTS13,
CACFD1,
PRSS23,
CLASRP,
FICD,
ERLIN2,
WIF1,
KLK8,
NXPH4,
NXPH3,
MAN1B1,
RDH13,
GLMP,
MGAT4B,
B4GALT7,
CFAP36,
IZUMO4,
CHST14,
CASC4,
VSIG4,
SCRG1,
TEX261,
SIGLEC11,
LACTB,
PGLYRP2,
SLC25A25
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员