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84263 HSDL2

84263

HSDL2

hydroxysteroid dehydrogenase like 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition hydroxysteroid dehydrogenase like 2

研究结论

Date Results Publications
2021-04-03 13:30:00 Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression. 32211805
2020-08-12 10:50:00 Hydroxysteroid dehydrogenase like 2 (HSDL2) expression was increased in papillary thyroid carcinoma (PTC) tissues and cells, which could promote tumor progression in vitro and in vivo. 31101684
2019-12-14 12:04:00 Study reported that HSDL2 was upregulated in two human bladder cancer cell lines 5637 and T24 compared to normal human urothelial cells. Lentiviral-mediated HSDL2 knockdown inhibited the proliferation and colony formation while promoted the apoptosis of human bladder cancer T24 cells in vitro and in nude mice T24 derived xenografts in vivo. Results suggest that HSDL2 plays an oncogenic role in bladder cancer. 31217732
2018-10-20 12:21:00 Study shows that HSDL2 upregulation is associated with ovarian cancer progression. HSDL2 knockdown inhibited cell proliferation, colony formation, motility, and tumorigenesis. 29894468
2017-03-04 12:43:00 High expression of HSDL2 is associated with glioma. 27658777

名称对应

Type IDs
Synonymous C9orf99, SDR13C1
Gene
UniProtKB-ID: HSDL2_HUMAN, A0A024R159_HUMAN
UniprotKB: Q6YN16, A0A024R159
UniParc: UPI000006F543, UPI0000039E52
EMBL: AL833735, AK289929, CH471105, AL162732, AK292486, BC095451, BC004331, AY093428
Ensembl: ENSG00000119471
KO: hsa:84263
Nucleutide sequences
EMBL-CDS: EAW59105.1, BAF85175.1, AAH04331.1, AAM14670.1, CAH56256.1, AAH95451.1, EAW59106.1, BAF82618.1, EAW59107.1
Gene_ORFName: hCG_28783
Ensembl_TRS: ENST00000398803, ENST00000398805
Protein sequencees
Ensembl_PRO: ENSP00000381785, ENSP00000381783
RefSeq: XP_016870694.1, XP_016870692.1, NP_115679.2, NP_001182751.1, XP_011517393.1, XP_016870693.1
Others
UniRef100: UniRef100_Q6YN16, UniRef100_A0A024R159
UniRef90: UniRef90_A0A667GY42, UniRef90_Q6YN16
UniRef50: UniRef50_A0A667GY42, UniRef50_Q6YN16
UniGene: Hs.59486
CCDS: CCDS43864.1, CCDS56582.1

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