| Type | Description |
|---|---|
| Definition | defective in cullin neddylation 1 domain containing 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 16:14:00 | All reported DCN1 inhibitors are able to induce remarkable accumulation of cullin 3 and its substrate NRF2, indicating therapeutic potential of DCN1 inhibitors for human diseases that may benefit from upregulation of cullin 3 and NRF2 | 31668094 |
| 2018-12-29 11:28:00 | evidence that DCNL5 may be involved in innate immunity, as it is a direct substrate of the kinase IKKalpha during immune signalling. | 29958295 |
| 2014-09-27 12:03:00 | SCCRO5 has oncogenic potential that requires its function as a component of the neddylation E3. Neddylation activity and nuclear localization of SCCRO5 are important for its in vivo function. | 24192928 |
| 2013-04-20 14:11:00 | Overexpression of DCUN1D5 is associated with laryngeal squamous cell carcinoma. | 23098533 |
| Type | IDs |
|---|---|
| Synonymous | SCCRO5 |
| Gene |
UniProtKB-ID:
DCNL5_HUMAN,
A0A024R3A2_HUMAN,
B4DP84_HUMAN
UniprotKB:
Q9BTE7,
A0A024R3A2,
B4DP84
UniParc:
UPI00017A781B,
UPI000006DE72
EMBL:
AK056993,
AY364246,
CH471065,
BC004169,
AK298227
Ensembl:
ENSG00000137692
KO:
hsa:84259
|
| Nucleutide sequences |
EMBL-CDS:
BAB71336.1,
AAQ76805.1,
AAH04169.1,
EAW67036.1,
EAW67037.1,
BAG60496.1
Gene_ORFName:
hCG_41261
Ensembl_TRS:
ENST00000260247
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000260247
RefSeq:
NP_001305668.1,
XP_016873893.1,
NP_115675.1,
NP_001305669.1,
NP_001305670.1
|
| Others |
UniRef100:
UniRef100_B4DP84,
UniRef100_Q9BTE7
UniRef90:
UniRef90_A0A2I0MCQ8,
UniRef90_Q9BTE7
UniRef50:
UniRef50_Q9BTE7
UniGene:
Hs.503716
CCDS:
CCDS8325.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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