| Type | Description |
|---|---|
| Definition | FLYWCH-type zinc finger 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 12:18:00 | we identify for the first time FLYWCH1 as a potential negative regulator of the downstream targets of the Wnt/beta-catenin pathway in AML cells. Hence, FLYWCH1 might be an intrinsic inhibitory factor of the oncogenic nuclear beta-catenin in AML cells. | 31167387 |
| 2019-08-31 12:26:00 | Study uncovers a new molecular mechanism by which FLYWCH1 with a possible tumor suppressive role represses beta-catenin-induced ZEB1 and increases cadherin-mediated cell attachment preventing colorectal cancer metastasis. | 30097457 |
| 2018-09-01 10:38:00 | FLYWCH1 variant of uncertain significance in candidate gene was identified in Familial Mitral Valve Prolapse. | 29762926 |
| 2016-01-30 11:44:00 | eQTLs acting across multiple tissues are significant carriers of inherited risk for CAD. FLYWCH1, PSORSIC3, and G3BP1 are novel master regulatory genes in CAD that may be suitable targets. | 25578447 |
| 2011-02-17 10:04:00 | Identifies the human FLYWCH1 protein (AB046772/KIAA1552) as containing five FLYWCH domain copies. | 15094203 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FWCH1_HUMAN
UniprotKB:
Q4VC44
UniParc:
UPI000013CE05,
UPI000006F97B,
UPI00001C0DD9,
UPI00001FF801,
UPI00001408BF
EMBL:
BC028572,
BC018712,
BC001973,
AB046772,
AK127235,
AL136585,
CH471112
Ensembl:
ENSG00000059122
KO:
hsa:84256
|
| Nucleutide sequences |
EMBL-CDS:
AAH01973.1,
EAW85450.1,
EAW85451.1,
AAH28572.1,
AAH18712.1,
BAC86896.1,
CAB66520.2,
BAB13378.1
Ensembl_TRS:
ENST00000253928,
ENST00000416288
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000399938,
ENSP00000253928
RefSeq:
XP_011521006.1,
XP_011521004.1,
NP_065963.1,
XP_016879261.1,
XP_011521003.1,
XP_006721025.1,
XP_011521005.1,
NP_001294997.1,
XP_011521009.1,
NP_115672.2,
XP_011521007.1
|
| Others |
UniRef100:
UniRef100_Q4VC44
UniRef90:
UniRef90_Q4VC44
UniRef50:
UniRef50_Q4VC44
UniGene:
Hs.655321
CCDS:
CCDS45390.1,
CCDS76809.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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