| Type | Description |
|---|---|
| Definition | rhomboid domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:53:00 | Silibinin suppresses epithelial-mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1. | 32528541 |
| 2020-06-13 10:13:00 | miR-145-5p was inversely related with RHBDD1 expression in CRC tissues. miR-145-5p was found to directly bind to RHBDD1 and restrained its expression in CRC cells. miR-145-5p overexpression repressed CRC cell proliferation, invasion, migration and induced apoptosis, and these effects were reversed by RHBDD1 upregulation. | 31693935 |
| 2020-04-04 10:40:00 | Bioinformatics analyses revealed that BioID hits of RHBDL4 overlap with factors related to protein stress at the ER, including proteins that interact with p97/VCP. PTP1B (protein-tyrosine phosphatase nonreceptor type 1, also called PTPN1) was also identified as a potential proximity factor and interactor of RHBDL4 | 31177093 |
| 2020-02-29 12:11:00 | RHBDD1 is a direct target of miR-138-5p. MiR-138-5p directly binds to the 3'-UTR of the RHBDD1 transcript to inhibit the expression of RHBDD1 in breast cancer cells. RHBDD1 and miR-138-5p appear to play an opposite role in breast cancer cell migration and invasion. | 31243644 |
| 2019-05-11 12:59:00 | RHBDD1 promotes breast cancer progression by regulating p-Akt and CDK2 protein levels | 30286765 |
| Type | IDs |
|---|---|
| Synonymous | RHBDL4, RRP4 |
| Gene |
UniProtKB-ID:
RHBL4_HUMAN
UniprotKB:
Q8TEB9
UniParc:
UPI0000047AE4,
UPI0000074695
EMBL:
AK074258,
BC089404,
AC010735,
AL512717,
BC062636,
BC101262,
BC101265,
BC101263,
AC073149,
BC101264,
BC111056,
AY640233,
BC027900
Ensembl:
ENSG00000144468
KO:
hsa:84236
|
| Nucleutide sequences |
EMBL-CDS:
AAI01265.1,
AAI01266.1,
BAB85031.1,
AAY24060.1,
AAU14246.1,
AAI01263.1,
CAC21658.2,
AAI01264.1,
AAH62636.1,
AAH27900.1,
AAI11057.1,
AAH89404.1
Gene_ORFName:
HSD50,
HSD-50
Ensembl_TRS:
ENST00000341329,
ENST00000392062
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344779,
ENSP00000375914
RefSeq:
XP_016860581.1,
NP_115652.2,
XP_016860574.1,
XP_016860582.1,
XP_016860583.1,
XP_016860579.1,
NP_001336001.1,
NP_001335998.1,
XP_016860584.1,
XP_016860572.1,
XP_016860577.1,
NP_001161080.1,
XP_016860575.1,
XP_016860573.1,
XP_016860576.1,
NP_001336000.1
|
| Others |
UniRef100:
UniRef100_Q8TEB9
UniRef90:
UniRef90_Q8TEB9
UniRef50:
UniRef50_Q8TEB9
UniGene:
Hs.471514
CCDS:
CCDS2464.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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