| Type | Description |
|---|---|
| Definition | fatty acyl-CoA reductase 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-01-31 10:19:00 | A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency. | 25439727 |
| 2014-02-22 12:13:00 | Expression of Far1 increased plasmalogen synthesis in wild-type Chinese hamster ovary cells, strongly suggesting that Far1 is a rate-limiting enzyme for plasmalogen synthesis. | 24108123 |
| 2010-04-19 11:07:00 | ether lipid biosynthesis in mammalian cells is regulated by a negative feedback mechanism that senses cellular plasmalogen levels and appropriately increases or decreases Far1 | 20071337 |
| 2010-01-21 00:00:00 | wax monoester synthesis in mammals involves a two step biosynthetic pathway catalyzed by fatty acyl-CoA reductase and wax synthase enzymes | 15220349 |
| 2010-01-21 00:00:00 | fatty alcohol synthesis in mammals is accomplished by two fatty acyl-CoA reductase isozymes that are expressed at high levels in tissues known to synthesize wax monoesters and ether lipids | 15220348 |
| Type | IDs |
|---|---|
| Synonymous | MLSTD2, PFCRD, SDR10E1 |
| Gene |
UniProtKB-ID:
FACR1_HUMAN
UniprotKB:
Q8WVX9
UniParc:
UPI00000477EF
EMBL:
AY423606,
AY600449,
AY358784,
CH471064,
BC017377,
CR936619
Ensembl:
ENSG00000197601
KO:
hsa:84188
|
| Nucleutide sequences |
EMBL-CDS:
AAH17377.1,
EAW68492.1,
EAW68493.1,
AAT42129.1,
CAI56762.1,
AAR84086.1,
AAQ89144.1
Gene_ORFName:
UNQ2423/PRO4981
Ensembl_TRS:
ENST00000354817
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000346874
RefSeq:
XP_011518702.1,
NP_115604.1
|
| Others |
UniRef100:
UniRef100_Q8WVX9
UniRef90:
UniRef90_Q8WVX9
UniRef50:
UniRef50_Q8WVX9
UniGene:
Hs.501991
CCDS:
CCDS7813.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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