| Type | Description |
|---|---|
| Definition | chromodomain helicase DNA binding protein 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 10:57:00 | Study shows that Chromodomain Helicase DNA-binding protein 6 (CHD6), distinct to other CHD enzymes, is stabilized during oxidative stress via reduced degradation and suggests that CHD6 is a key regulator of the oxidative DNA damage response. | 30651562 |
| 2017-08-05 11:38:00 | Data suggest that CHD6 and CHD7 both bind with high affinity to short linker DNA, whereas CHD8 requires longer DNA for binding; thus, CHD8 slides nucleosomes into positions with more flanking linker DNA than CHD7; CHD6 disrupts nucleosomes in a distinct non-sliding manner. | 28533432 |
| 2016-01-30 11:26:00 | The role of CHD6 in regulating the chromatin topology of CFTR as an exemplary genetic model for this mechanism was described. | 25631877 |
| 2015-03-16 13:18:00 | CHD6 regulates the topology of the CFTR locus | 25631877 |
| 2013-05-18 10:30:00 | These data indicate that CHD6 degradation is a general effect exerted by influenza A viruses and suggest that this viral repressor may play an important inhibitory role since degradation and accumulation into inactive chromatin occur during the infection. | 23408615 |
| Type | IDs |
|---|---|
| Synonymous | CHD-6, CHD5, RIGB |
| Gene |
UniProtKB-ID:
CHD6_HUMAN
UniprotKB:
Q8TD26
UniParc:
UPI0000168656,
UPI0001D1473F,
UPI0000470956
EMBL:
AF525085,
AB037756,
AL031669,
AK026022,
AL121674,
AL031667,
BC040016,
BC021907,
AY034072,
BC039860
Ensembl:
ENSG00000124177
KO:
hsa:84181
|
| Nucleutide sequences |
EMBL-CDS:
BAB15325.1,
AAK56405.1,
AAH21907.1,
BAA92573.2,
AAN59903.1
Ensembl_TRS:
ENST00000373222,
ENST00000373233
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362319,
ENSP00000362330
RefSeq:
XP_016883591.1,
XP_016883588.1,
XP_011527384.1,
XP_016883589.1,
XP_016883590.1,
NP_115597.3,
XP_016883593.1,
XP_005260633.1,
XP_011527382.1,
XP_005260630.1,
XP_016883592.1
|
| Others |
UniRef100:
UniRef100_Q8TD26
UniRef90:
UniRef90_Q8TD26
UniRef50:
UniRef50_Q8TD26
UniGene:
Hs.740645
CCDS:
CCDS13317.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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