| Type | Description |
|---|---|
| Definition | lysine acetyltransferase 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:13:00 | Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability. | 31794431 |
| 2020-09-19 16:27:00 | Histone Acetyltransferase MOF Orchestrates Outcomes at the Crossroad of Oncogenesis, DNA Damage Response, Proliferation, and Stem Cell Development. | 32661120 |
| 2020-06-06 10:30:00 | Human MOF was highly expressed in endometrial carcinoma and associated with proliferation. High expression of human MOF was associated with late-stage cancer, lymph node metastasis and short survival time, and it was also an independent prognostic risk factor for endometrial carcinoma. | 31990345 |
| 2020-05-09 10:29:00 | KAT8 is down-regulating virus-induced IFN-I production by acetylating the transcription factor IRF3 at lysine 359, inhibiting the recruitment of IRF3 to IFN-I promoters, and decreasing its transcriptional activity. | 30842237 |
| 2019-11-02 10:52:00 | MOF promotes endometrial cancer cell growth and proliferation in vitro and in vivo. Clinical evidence indicates that expression MOF is decreased and positively correlated with that of ER-alpha in endometrial cancer tissues. | 30598260 |
| Type | IDs |
|---|---|
| Synonymous | MOF, MYST1, ZC2HC8, hMOF |
| Gene |
UniProtKB-ID:
KAT8_HUMAN
UniprotKB:
Q9H7Z6
UniParc:
UPI000004FA7B,
UPI00001B02B6
EMBL:
AK021872,
AC135050,
AK024102,
BC037773,
AK291106,
CH471192,
AC009088,
AF217501,
AF289578,
AL050395,
AF260665
Ensembl:
ENSG00000103510
KO:
hsa:84148
|
| Nucleutide sequences |
EMBL-CDS:
BAB13924.1,
AAL55762.1,
EAW52158.1,
AAF72665.2,
AAH37773.1,
CAH56416.1,
BAB14827.1,
EAW52157.1,
AAL56648.1,
BAF83795.1
Gene_ORFName:
PP7073
Ensembl_TRS:
ENST00000219797,
ENST00000543774,
ENST00000448516
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000406037,
ENSP00000456933,
ENSP00000219797
RefSeq:
XP_011544272.1,
NP_892003.2,
NP_115564.2,
XP_011544273.1
|
| Others |
UniRef100:
UniRef100_Q9H7Z6
UniRef90:
UniRef90_Q9H7Z6
UniRef50:
UniRef50_Q9H7Z6
UniGene:
Hs.533803
CCDS:
CCDS10706.1,
CCDS45468.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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