| Type | Description |
|---|---|
| Definition | early endosome antigen 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:17:00 | Here, using EGF/EGFR endocytosis as a model and confocal microscopy of fixed and live cells, we provide evidence favoring EEA1-vesicles being pre-existed vesicular compartment, that maintains its resident proteins' level and is sensitive to biosynthetic, but not endocytic pathway disturbance. | 32357161 |
| 2019-07-06 10:53:00 | Rab5C and EEA1 in the early endosomal pathway, and Rab7A and lysobisphosphatidic acid in the late endosomal pathway, are important for trafficking of phosphorothioate Antisense oligonucleotides and facilitate their escape from endolysosomal compartments after Stabilin-mediated internalization. | 29437530 |
| 2018-09-29 10:49:00 | This also suggests that this pathway is involved in EEA1-vesicles biogenesis. | 30188634 |
| 2018-07-14 10:38:00 | identification of allergic bronchopulmonary aspergillosis -associated variants in EEA that have functional effects on macrophage phagocytosis and phagolysosome acidification of A. fumigatus conidia. | 29547649 |
| 2017-03-18 12:46:00 | results suggest a new mechanism in which Rab5 induces a change in flexibility of EEA1, generating an entropic collapse force that pulls the captured vesicle towards the target membrane to initiate docking and membrane fusion | 27556945 |
| Type | IDs |
|---|---|
| Synonymous | MST105, MSTP105, ZFYVE2 |
| Gene |
UniProtKB-ID:
EEA1_HUMAN
UniprotKB:
Q15075
UniParc:
UPI000013C754
EMBL:
L40157,
AC026111,
AC021646,
AC016136,
X78998
Ensembl:
ENSG00000102189
KO:
hsa:8411
|
| Nucleutide sequences |
EMBL-CDS:
AAA79121.1,
CAA55632.1
Ensembl_TRS:
ENST00000322349
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000317955
RefSeq:
XP_011537117.1,
NP_003557.3,
XP_016875507.1,
XP_011537116.1
|
| Others |
UniRef100:
UniRef100_Q15075
UniRef90:
UniRef90_Q15075
UniRef50:
UniRef50_Q15075
UniGene:
Hs.567367
CCDS:
CCDS31874.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员