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84106 PRAM1

84106

PRAM1

PML-RARA regulated adaptor molecule 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition PML-RARA regulated adaptor molecule 1

研究结论

Date Results Publications
2019-06-01 11:11:00 we diagnosed a spinal promyelocytic sarcoma as a manifestation of acute promyelocytic leukaemia with M3 morphology according to the French-American-British classification with t(15;17)(q22;q21) and PML-RARA fusion gene 28431836
2018-11-10 10:09:00 This study establishes PML as an important regulator of NF-kappaB and demonstrates that PML-RARalpha dysregulates NF-kappaB. 28317833
2016-04-09 10:36:00 Our results show that the pretreatment PML-RARA molecular burden could therefore be used to improve risk stratification in order to develop more individualized treatment regimens for high-risk APL cases. 25944686
2016-02-27 11:23:00 The 3-plex RT-qPCR assay is a specific, sensitive, stable, and cost-effective method that can be used for the rapid diagnosis and treatment monitoring of acute promyelocytic leukemia with PML-RARa 25815789
2015-05-23 10:05:00 The MIR125B1-mediated blockade of PML-RARA proteolysis was regulated via an autophagy-lysosomal pathway, contributing to the inhibition of acute promyelocytic leukemia differentiation. 25126724

名称对应

Type IDs
Synonymous PML-RAR, PRAM-1
Gene
UniProtKB-ID: PRAM_HUMAN
UniprotKB: Q96QH2
UniParc: UPI00001AE786
EMBL: AC092298, BC028012, AC136469, AJ272324
Ensembl: ENSG00000133246
KO: hsa:84106
Nucleutide sequences
EMBL-CDS: AAH28012.1, CAC17767.1
Ensembl_TRS: ENST00000423345
Protein sequencees
Ensembl_PRO: ENSP00000408342
RefSeq: XP_005272559.1, XP_011526655.1, NP_115528.4, XP_011526654.1
Others
UniRef100: UniRef100_Q96QH2
UniRef90: UniRef90_Q96QH2
UniRef50: UniRef50_Q96QH2
UniGene: Hs.465812
CCDS: CCDS45954.2

全选

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