| Type | Description |
|---|---|
| Definition | PML-RARA regulated adaptor molecule 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-01 11:11:00 | we diagnosed a spinal promyelocytic sarcoma as a manifestation of acute promyelocytic leukaemia with M3 morphology according to the French-American-British classification with t(15;17)(q22;q21) and PML-RARA fusion gene | 28431836 |
| 2018-11-10 10:09:00 | This study establishes PML as an important regulator of NF-kappaB and demonstrates that PML-RARalpha dysregulates NF-kappaB. | 28317833 |
| 2016-04-09 10:36:00 | Our results show that the pretreatment PML-RARA molecular burden could therefore be used to improve risk stratification in order to develop more individualized treatment regimens for high-risk APL cases. | 25944686 |
| 2016-02-27 11:23:00 | The 3-plex RT-qPCR assay is a specific, sensitive, stable, and cost-effective method that can be used for the rapid diagnosis and treatment monitoring of acute promyelocytic leukemia with PML-RARa | 25815789 |
| 2015-05-23 10:05:00 | The MIR125B1-mediated blockade of PML-RARA proteolysis was regulated via an autophagy-lysosomal pathway, contributing to the inhibition of acute promyelocytic leukemia differentiation. | 25126724 |
| Type | IDs |
|---|---|
| Synonymous | PML-RAR, PRAM-1 |
| Gene |
UniProtKB-ID:
PRAM_HUMAN
UniprotKB:
Q96QH2
UniParc:
UPI00001AE786
EMBL:
AC092298,
BC028012,
AC136469,
AJ272324
Ensembl:
ENSG00000133246
KO:
hsa:84106
|
| Nucleutide sequences |
EMBL-CDS:
AAH28012.1,
CAC17767.1
Ensembl_TRS:
ENST00000423345
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000408342
RefSeq:
XP_005272559.1,
XP_011526655.1,
NP_115528.4,
XP_011526654.1
|
| Others |
UniRef100:
UniRef100_Q96QH2
UniRef90:
UniRef90_Q96QH2
UniRef50:
UniRef50_Q96QH2
UniGene:
Hs.465812
CCDS:
CCDS45954.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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