| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 44 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:31:00 | USP44 suppresses proliferation and enhances apoptosis in colorectal cancer cells by inactivating the Wnt/beta-catenin pathway via Axin1 deubiquitination. | 32285989 |
| 2020-11-21 13:14:00 | Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinoma. | 32164618 |
| 2020-08-01 14:20:00 | Existence of circFOXO3-miR-143-3p-USP44 axis in GC cells was confirmed by RNA-binding protein immunoprecipitation, luciferase reporter assay, and an RNA pull-down experiments. All the data indicate that circFOXO3 promotes GC cell proliferation and migration by upregulating USP44 expression via targeting of miR-143-3p. | 32445925 |
| 2020-05-02 10:51:00 | identified USP44 as a positive regulator of MITA; USP44 is recruited to MITA following DNA virus infection and removes K48-linked polyubiquitin moieties from MITA at K236, therefore prevents MITA from proteasome mediated degradation; findings suggest that USP44 plays a specific and critical role in the regulation of innate immune response against DNA viruses | 31968013 |
| 2020-02-15 13:44:00 | USP44 inhibited AKT signaling by stabilizing PTEN in non-small cell lung cancer cells. | 31197957 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UBP44_HUMAN,
A0A024RBD7_HUMAN
UniprotKB:
Q9H0E7,
A0A024RBD7
UniParc:
UPI000013CFDB
EMBL:
AC018475,
AK315697,
BC030704,
CH471054,
AL136825
Ensembl:
ENSG00000136014
KO:
hsa:84101
|
| Nucleutide sequences |
EMBL-CDS:
CAB66759.1,
AAH30704.1,
BAG38060.1,
EAW97542.1,
EAW97541.1,
EAW97540.1
Gene_ORFName:
hCG_1642341
Ensembl_TRS:
ENST00000393091,
ENST00000258499,
ENST00000537435
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258499,
ENSP00000442629,
ENSP00000376806
RefSeq:
XP_011537104.1,
XP_011537102.1,
XP_005269229.1,
NP_001334865.1,
XP_016875501.1,
XP_011537106.1,
NP_001265322.1,
XP_011537105.1,
XP_005269230.1,
NP_001035862.1,
XP_016875499.1,
NP_115523.2,
XP_011537107.1,
NP_001334866.1,
XP_005269231.1,
XP_011537108.1,
XP_011537103.1
|
| Others |
UniRef100:
UniRef100_Q9H0E7
UniRef90:
UniRef90_Q9H0E7
UniRef50:
UniRef50_Q9H0E7
UniGene:
Hs.646421,
Hs.710121
CCDS:
CCDS9053.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Instituto Universitario de Oncología |
2 |
| 2 |
Molecular Genome Analysis, German Cancer Research Center, 69120 Heidelberg, Germany. s.wiemann@dkfz.de |
2 |
| 3 |
The University of Texas MD Anderson Cancer Center |
2 |
| 4 |
Max Planck Institute of Biochemistry |
1 |
| 5 |
Biogen Inc., 250 Binney Street, Cambridge, Massachusetts 02142, USA. |
1 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
J Wade Harper |
3 |
| 2 |
Sumio Sugano |
3 |
| 3 |
Yutaka Suzuki |
3 |
| 4 |
M Bento Soares |
3 |
| 5 |
Ying Zhang |
3 |