| Type | Description |
|---|---|
| Definition | ubiquitously expressed prefoldin like chaperone |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:14:00 | UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy. | 33782410 |
| 2021-01-16 15:56:00 | The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-kappaB signaling pathway. | 33010352 |
| 2020-02-22 10:07:00 | The ubiquitous expressed transcript (UXT) interacts with the polycomb repressive complex 2 (PRC2) through directly binding to the enhancer of zeste homolog 2 (EZH2) and suppressor of zeste 12 homolog (SUZ12) in the nucleus. Knockdown of UXT inhibits proliferation, colony formation, migration and invasion of renal cancer cells, in an EZH2-dependent manner. UXT expression is upregulated in clear cell renal cell carcinoma. | 31481081 |
| 2017-12-30 12:24:00 | UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast | 28106301 |
| 2017-08-05 10:45:00 | EZH1, SUZ12 and UXT work synergistically to regulate pathway activation in the nucleus. | 27127229 |
| Type | IDs |
|---|---|
| Synonymous | ART-27, STAP1 |
| Gene |
UniProtKB-ID:
UXT_HUMAN
UniprotKB:
Q9UBK9
UniParc:
UPI0000044699,
UPI0000044696
EMBL:
AF083242,
AF092737,
AK312072,
BC008890,
BC000720,
AF083241,
CH471164,
AL009172
Ensembl:
ENSG00000126756
KO:
hsa:8409
|
| Nucleutide sequences |
EMBL-CDS:
AAD39839.1,
AAD28698.1,
AAD39840.1,
EAW59325.1,
EAW59326.1,
AAH08890.1,
AAH00720.1,
BAG35008.1
Gene_ORFName:
HSPC024
Ensembl_TRS:
ENST00000333119,
ENST00000335890
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000327797,
ENSP00000337393
RefSeq:
NP_705582.1,
NP_004173.1
|
| Others |
UniRef100:
UniRef100_Q9UBK9
UniRef90:
UniRef90_Q9UBK9
UniRef50:
UniRef50_Q9UBK9
UniGene:
Hs.172791,
Hs.735566
CCDS:
CCDS14284.1,
CCDS14285.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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