| Type | Description |
|---|---|
| Definition | transketolase like 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 12:01:00 | Homology modelling of TKTL1 and TKTL2 using transketolase (TKT) as template, revealed that both could assume a folded structure like TKT. TKTL1/2 presented a cleft of suitable dimensions between the homodimer surfaces that could accommodate the co-factor-substrate. An appropriate cavity and a hydrophobic nodule were also present in TKTL1/2 and implicated in aminopyrimidine and thiazole ring binding in TKT, respectively. | 30646877 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20800603 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TKTL2_HUMAN,
A0A140VKC2_HUMAN
UniprotKB:
Q9H0I9,
A0A140VKC2
UniParc:
UPI0000037C67
EMBL:
AL136779,
HM005662,
CH471056,
AK057325,
CR533560,
BC028707,
BC142943,
BC125101
Ensembl:
ENSG00000151005
KO:
hsa:84076
|
| Nucleutide sequences |
EMBL-CDS:
BAB71427.1,
CAG38591.1,
AAI25102.1,
CAB66713.1,
AAH28707.4,
AAI42944.1,
AEE61259.1,
EAX04838.1
Gene_ORFName:
hCG_1645659
Ensembl_TRS:
ENST00000280605
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000280605
RefSeq:
NP_115512.3
|
| Others |
UniRef100:
UniRef100_Q9H0I9
UniRef90:
UniRef90_Q9H0I9
UniRef50:
UniRef50_Q9H0I9
UniGene:
Hs.303923
CCDS:
CCDS3805.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30646877 |
The human transketolase-like proteins TKTL1 and TKTL2 are bona fide transketolases. BMC Struct. Biol. Gaurang P Deshpande , Hugh-George Patterton , M Faadiel Essop |
2019-01-15 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20800603 |
Mutat. Res. Friederike Flachsbart , Andre Franke , Rabea Kleindorp , Amke Caliebe , Hélène Blanché , Stefan Schreiber , Almut Nebel |
2010-12-10 |
PDCD6IP,
INSL5,
CHAF1A,
HMGXB4,
SMC4,
PRG4,
COQ7,
SLC35B1,
TLR6,
GLRX3,
IQGAP2,
NEU3,
ME3,
MRPS30,
SPINK5,
DIDO1,
CHI3L1,
NUDT6,
CHIT1,
RASSF1,
BIRC8,
IL17F,
HELQ,
NLRP3,
RNF157,
SLC5A11,
GALNT15,
GSTO2,
CMA1,
GABPB2,
ADH4,
IQGAP3,
OSR1,
ADH7,
GLYCTK,
UGT3A1,
PXDNL,
CRYGB,
BNIPL,
CTSG,
KLB,
PRUNE2,
DCC,
HFM1,
CLYBL,
DLAT,
DNASE1,
DNASE1L3,
AGL,
TRDMT1,
DUSP6,
EGF,
NLRP7,
SLC5A9,
EMP1,
ENO3,
ERBB3,
ESR1,
FANCA,
FANCE,
PTK2B,
A2M,
FGL1,
HSPA4L,
NLRP1,
CARD8,
ATF6,
ACIN1,
FOXM1,
SETX,
SWAP70,
FLG,
FLT3,
MAN2B2,
KHNYN,
ARHGEF12,
SIRT5,
SIRT3,
ORC3,
PPP1R15A,
POLA2,
FRK,
FUCA1,
FUCA2,
FUT2,
GCA,
GALC,
ASF1A,
GALT,
GANC,
GAPDH,
LRIT1,
FBXO5,
GALNT8,
GBGT1,
GBE1,
GCKR,
GFRA2,
GIP
|
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 16381901 |
Nucleic Acids Res. Alexander Mehrle , Heiko Rosenfelder , Ingo Schupp , Coral del Val , Dorit Arlt , Florian Hahne , Stephanie Bechtel , Jeremy Simpson , Oliver Hofmann , Winston Hide , Karl-Heinz Glatting , Wolfgang Huber , Rainer Pepperkok , Annemarie Poustka , Stefan Wiemann |
2006-01-01 |
AKT3,
ZBTB33,
CMC4,
DNAJB6,
C16orf95,
KIF20A,
ACTR1A,
BCAP31,
FARP1,
LPCAT3,
CDK2,
CDK7,
COQ7,
SPRY2,
STAM2,
CDKN1A,
CDKN1B,
PAK4,
CDKN2B,
RACK1,
IFITM3,
TADA3,
SEMA4F,
SORBS1,
CDC42EP3,
PDLIM5,
ATP5L,
GNB5,
CETN2,
NUDC,
CTSC,
RUVBL2,
SPIN1,
YWHAQ,
ASCC3,
MAPRE2,
SLC38A3,
NUDT21,
C10orf10,
TRIOBP,
PRSS23,
CDC37,
C14orf1,
FAM107A,
POLI,
TREX2,
EGLN2,
USP18,
CHRM2,
COPE,
GABARAPL2,
SYNPO,
ZBED9,
OSBPL5,
GPRASP2,
FCHO2,
DHRS1,
LRRC58,
LYSMD3,
LRRC3B,
RAB39B,
MIA2,
SSX2IP,
GALNT15,
CLCN3,
PIK3AP1,
MORN4,
CLIC2,
TC2N,
ZG16B,
MOB3A,
C19orf47,
LRRC39,
TMEM150A,
BBS5,
PLEKHH2,
OSR1,
COPB1,
SYNPR,
TMPRSS11B,
NUDCD2,
NCOA7,
ZNF786,
MTPN,
ZNF572,
ABRA,
PASD1,
RNF32,
MROH8,
RPL10L,
SRXN1,
CRYAB,
MIB2,
FAM76B,
ZNF664,
CPNE8,
SLFN13,
SCGB1C1,
ZNF555
|
| 16189514 |
Towards a proteome-scale map of the human protein-protein interaction network. Nature Jean-François Rual , Kavitha Venkatesan , Tong Hao , Tomoko Hirozane-Kishikawa , Amélie Dricot , Ning Li , Gabriel F Berriz , Francis D Gibbons , Matija Dreze , Nono Ayivi-Guedehoussou , Niels Klitgord , Christophe Simon , Mike Boxem , Stuart Milstein , Jennifer Rosenberg , Debra S Goldberg , Lan V Zhang , Sharyl L Wong , Giovanni Franklin , Siming Li , Joanna S Albala , Janghoo Lim , Carlene Fraughton , Estelle Llamosas , Sebiha Cevik , Camille Bex , Philippe Lamesch , Robert S Sikorski , Jean Vandenhaute , Huda Y Zoghbi , Alex Smolyar , Stephanie Bosak , Reynaldo Sequerra , Lynn Doucette-Stamm , Michael E Cusick , David E Hill , Frederick P Roth , Marc Vidal |
2005-10-20 | - |
| 15489336 |
From ORFeome to biology: a functional genomics pipeline. Genome Res. Stefan Wiemann , Dorit Arlt , Wolfgang Huber , Ruth Wellenreuther , Simone Schleeger , Alexander Mehrle , Stephanie Bechtel , Mamatha Sauermann , Ulrike Korf , Rainer Pepperkok , Holger Sültmann , Annemarie Poustka |
2004-10-01 |
AKT3,
ZBTB33,
CMC4,
DNAJB6,
C16orf95,
KIF20A,
ACTR1A,
BCAP31,
FARP1,
LPCAT3,
CDK2,
CDK7,
COQ7,
SPRY2,
STAM2,
CDKN1A,
CDKN1B,
PAK4,
CDKN2B,
RACK1,
IFITM3,
TADA3,
SEMA4F,
SORBS1,
CDC42EP3,
PDLIM5,
ATP5L,
GNB5,
CETN2,
NUDC,
CTSC,
RUVBL2,
SPIN1,
YWHAQ,
ASCC3,
MAPRE2,
SLC38A3,
NUDT21,
C10orf10,
TRIOBP,
PRSS23,
CDC37,
C14orf1,
FAM107A,
POLI,
TREX2,
EGLN2,
USP18,
CHRM2,
COPE,
GABARAPL2,
SYNPO,
ZBED9,
OSBPL5,
GPRASP2,
FCHO2,
DHRS1,
LRRC58,
LYSMD3,
LRRC3B,
RAB39B,
MIA2,
SSX2IP,
GALNT15,
CLCN3,
PIK3AP1,
MORN4,
CLIC2,
TC2N,
ZG16B,
MOB3A,
C19orf47,
LRRC39,
TMEM150A,
BBS5,
PLEKHH2,
OSR1,
COPB1,
SYNPR,
TMPRSS11B,
NUDCD2,
NCOA7,
ZNF786,
MTPN,
ZNF572,
ABRA,
PASD1,
RNF32,
MROH8,
RPL10L,
SRXN1,
CRYAB,
MIB2,
FAM76B,
ZNF664,
CPNE8,
SLFN13,
SCGB1C1,
ZNF555
|
| 14702039 |
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano |
2004-01-01 |
Slc9a8,
Nefm,
Hfe2,
AKT3,
ZBTB11-AS1,
LOC100034248,
PDZK1P1,
DDTL,
LOC100049716,
ACOT8,
GNPDA1,
ZBTB33,
GTF2IP4,
POM121C,
ZSCAN30,
SRA1,
SNORD123,
UCKL1-AS1,
ZGLP1,
LOC100125918,
LINC00322,
LOC100127940,
HECW1-IT1,
LOC100127955,
LOC100127972,
LOC100127974,
FAM229A,
LOC100128076,
STAU2-AS1,
LOC100128164,
TMPO-AS1,
LOC100128219,
LOC100128239,
LOC100128253,
TNK2-AS1,
DNM1P35,
LOC100128288,
DLG5-AS1,
LOC100128310,
TRAPPC3L,
FAM83H-AS1,
LOC100128361,
LOC100128364,
FAM225B,
LOC100128386,
LOC100128398,
ASTN2-AS1,
C1orf132,
MYHAS,
LOC100128651,
LINC00476,
SRRM2-AS1,
GPR158-AS1,
LINC01165,
VPS9D1-AS1,
FAM66B,
GATA6-AS1,
LINC01310,
LOC100128979,
LOC100128988,
LOC100129034,
SEMA3F-AS1,
UNQ6494,
LOC100129115,
KHDC1L,
LOC100129175,
MATN1-AS1,
SLC39A12-AS1,
LOC100129297,
LOC100129312,
LINC00484,
LOC100129397,
LOC100129406,
DDC-AS1,
LOC100129434,
LOC100129447,
LOC100129455,
LYRM4-AS1,
ZNF37BP,
LOC100129516,
LOC100129518,
LOC100129540,
LOC100129572,
FAM47E,
LOC100129620,
LOC100129648,
C9orf173-AS1,
LOC100129775,
SLC25A21-AS1,
PCOLCE-AS1,
SCOC-AS1,
LOC100129884,
LOC100129894,
LOC100129917,
LOC100129935,
LOC100130078,
LOC100130111,
MAPT-IT1,
MIR124-2HG
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员