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8406 SRPX

8406

SRPX

sushi repeat containing protein X-linked

protein-coding

Homo sapiens

基因描述

Type Description
Definition sushi repeat containing protein X-linked

研究结论

Date Results Publications
2020-04-04 11:33:00 the findings of the present study suggest that targeting the Cancerassociated fibroblasts genes, SRPX and HMCN1, can inhibit ovarian cancer migration and invasion. 31638245
2018-06-30 10:13:00 SRPX1 co-accumulated with Abeta deposits in cerebral blood vessels of all autopsied cases with severe cerebral amyloid angiopathy (CAA); no SRPX1 co-accumulated with Abeta deposits in senile plaques. Furthermore, we demonstrated that both Abeta40 and Abeta42 bound to SRPX1 in vitro and enhanced SRPX1 expression in primary cultures of cerebrovascular smooth muscle cells. SRPX1 enhanced caspase activity induced by Abeta40. 28478503
2013-05-28 14:51:00 The SRPX protein contains the P-DUDES structural domain in its C-terminal region. This domain has significant albeit remote sequence similarity to thioredoxin-like domains, and is predicted to possess an oxidoreductase function. 209648
2010-07-12 11:04:00 PELO is subcellularly localized at the actin cytoskeleton, interacts with HAX1, EIF3G and SRPX proteins and that this interaction occurs at the cytoskeleton; this interaction may facilitate PELO to detect and degrade aberrant mRNAs. 20406461
2010-01-22 12:35:00 An apoptosis-inducing protein localized in the endoplasmic reticulum which increases efficiency of apoptosis 15021917

名称对应

Type IDs
Synonymous DRS, ETX1, HEL-S-83p, SRPX1
Gene
UniProtKB-ID: SRPX_HUMAN
UniprotKB: P78539
UniParc: UPI000002B436, UPI0001C0B384, UPI0000D69BA0, UPI0000135F5C, UPI00017A7722
EMBL: AK125542, BC020684, AK298802, AL121578, S82496, AK289430, CH471141, AL133494, U78093, U61374, AL627246, AK293127, AL606748
Ensembl: ENSG00000101955
KO: hsa:8406
Nucleutide sequences
EMBL-CDS: AAH20684.1, EAW59447.1, AAB37378.1, BAF82119.1, BAG54210.1, AAB40715.1, BAG56679.1, BAG60937.1, AAB37379.1, AAB36685.1
Ensembl_TRS: ENST00000432886, ENST00000544439, ENST00000378533, ENST00000538295
Protein sequencees
Ensembl_PRO: ENSP00000411165, ENSP00000440758, ENSP00000367794, ENSP00000445034
RefSeq: NP_001164222.1, NP_006298.1, NP_001164221.1, NP_001164223.1, XP_016885382.1
Others
UniRef100: UniRef100_P78539
UniRef90: UniRef90_P78539
UniRef50: UniRef50_P78539
UniGene: Hs.15154
CCDS: CCDS14245.1, CCDS55401.1, CCDS55400.1, CCDS55402.1

全选

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