Type | Description |
---|---|
Definition | sushi repeat containing protein X-linked |
Date | Results | Publications |
---|---|---|
2020-04-04 11:33:00 | the findings of the present study suggest that targeting the Cancerassociated fibroblasts genes, SRPX and HMCN1, can inhibit ovarian cancer migration and invasion. | 31638245 |
2018-06-30 10:13:00 | SRPX1 co-accumulated with Abeta deposits in cerebral blood vessels of all autopsied cases with severe cerebral amyloid angiopathy (CAA); no SRPX1 co-accumulated with Abeta deposits in senile plaques. Furthermore, we demonstrated that both Abeta40 and Abeta42 bound to SRPX1 in vitro and enhanced SRPX1 expression in primary cultures of cerebrovascular smooth muscle cells. SRPX1 enhanced caspase activity induced by Abeta40. | 28478503 |
2013-05-28 14:51:00 | The SRPX protein contains the P-DUDES structural domain in its C-terminal region. This domain has significant albeit remote sequence similarity to thioredoxin-like domains, and is predicted to possess an oxidoreductase function. | 209648 |
2010-07-12 11:04:00 | PELO is subcellularly localized at the actin cytoskeleton, interacts with HAX1, EIF3G and SRPX proteins and that this interaction occurs at the cytoskeleton; this interaction may facilitate PELO to detect and degrade aberrant mRNAs. | 20406461 |
2010-01-22 12:35:00 | An apoptosis-inducing protein localized in the endoplasmic reticulum which increases efficiency of apoptosis | 15021917 |
Type | IDs |
---|---|
Synonymous | DRS, ETX1, HEL-S-83p, SRPX1 |
Gene |
UniProtKB-ID:
SRPX_HUMAN
UniprotKB:
P78539
UniParc:
UPI000002B436,
UPI0001C0B384,
UPI0000D69BA0,
UPI0000135F5C,
UPI00017A7722
EMBL:
AK125542,
BC020684,
AK298802,
AL121578,
S82496,
AK289430,
CH471141,
AL133494,
U78093,
U61374,
AL627246,
AK293127,
AL606748
Ensembl:
ENSG00000101955
KO:
hsa:8406
|
Nucleutide sequences |
EMBL-CDS:
AAH20684.1,
EAW59447.1,
AAB37378.1,
BAF82119.1,
BAG54210.1,
AAB40715.1,
BAG56679.1,
BAG60937.1,
AAB37379.1,
AAB36685.1
Ensembl_TRS:
ENST00000432886,
ENST00000544439,
ENST00000378533,
ENST00000538295
|
Protein sequencees |
Ensembl_PRO:
ENSP00000411165,
ENSP00000440758,
ENSP00000367794,
ENSP00000445034
RefSeq:
NP_001164222.1,
NP_006298.1,
NP_001164221.1,
NP_001164223.1,
XP_016885382.1
|
Others |
UniRef100:
UniRef100_P78539
UniRef90:
UniRef90_P78539
UniRef50:
UniRef50_P78539
UniGene:
Hs.15154
CCDS:
CCDS14245.1,
CCDS55401.1,
CCDS55400.1,
CCDS55402.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
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Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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