MND1 - meiotic nuclear divisions 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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84057 MND1

基因描述

Type	Description
Definition	meiotic nuclear divisions 1

研究结论

Date	Results	Publications
2020-06-27 10:18:00	Assuming the mouse model accurately reflects the impact of this variant in humans, rs140107488 appears to be a benign allele that can be eliminated or de-prioritized in clinical genomic analyses of infertility patients.	31393579
2013-09-28 11:53:00	Data indicate that the positive expression of studied genes fertilization rate for GAPDHS positive subset was 66%, ACR - 71%, - 68%, MND1 - 70%, pregnancy rates were 8%, 6%, 18% and 36% respectively.	23675907
2010-06-30 22:06:00	Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)	20379614
2010-01-21 00:00:00	Data suggest that the human TBPIP/Hop2-Mnd1 complex may ensure proper pairing between homologous chromosomes through its stimulation of strand exchange during meiosis.	16407260

名称对应

Type	IDs
Synonymous	GAJ
Gene	UniProtKB-ID: MND1_HUMAN, A0A087WTC6_HUMAN UniprotKB: Q9BWT6, A0A087WTC6 UniParc: UPI00004133F5, UPI000006EAB8 EMBL: AC013477, AY028916, AK312172, CH471056, BC032142 Ensembl: ENSG00000121211 KO: hsa:84057
Nucleutide sequences	EMBL-CDS: BAG35106.1, AAK26168.1, EAX04965.1, AAH32142.1, EAX04964.1 Ensembl_TRS: ENST00000240488, ENST00000622785
Protein sequencees	Ensembl_PRO: ENSP00000240488, ENSP00000477758 RefSeq: XP_016864177.1, NP_001240790.1, XP_005263332.1, XP_024310010.1, NP_115493.1
Others	UniRef100: UniRef100_A0A087WTC6, UniRef100_Q9BWT6 UniRef90: UniRef90_A0A087WTC6, UniRef90_Q9BWT6 UniRef50: UniRef50_F1PV98, UniRef50_Q9BWT6 UniGene: Hs.294088 CCDS: CCDS3782.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31393579	A predicted deleterious allele of the essential meiosis gene MND1, present in ~â3% of East Asians, does not disrupt reproduction in mice. Mol Hum Reprod Tina N Tran , Julianna Martinez , John C Schimenti	2019-10-28	-
30021884	Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck	2018-10-01	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
26496610	A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , JÃ¼rgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , JÃ¶rg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann	2015-10-22	Cep85l, Rcc1, Zbtb48, Bsdc1, Kifc1, Ccp110, Ints4, Slc6a8, Cenpi, Nup107, Xpo1, Fbxw11, Tubg1, Csnk1d, Bap1, Ptpn23, Tecpr2, Slain1, Ankrd28, Prkaa1, Espl1, Gbf1, Cdc20, Cenpf, Trip11, Mbd5, Kif22, Dut, Srsf1, Actb, Spred2, Akt2, Mta1, Tgs1, Pip4k2c, Ankfy1, Apc, Ar, Rhoa, Atp2a2, Atp5a1, Atp7a, Cep131, Bach1, Bcl7c, Bmpr1a, Brca1, Bub1, Bub1b, C1qbp, Anxa2, Calu, Cbx1, Cbx4, Cct2, Cct3, Cct4, Cct7, Cct8, Cd2ap, Cdk1, Cdc37, Cdh1, Chek1, Cit, Copa, Crebbp, Cry1, Csk, Smc3, Dctn1, Ddb1, Cdk2ap1, Mapre1, Ect2, Eef1a1, Eif3a, Mark2, Evpl, Ewsr1, Wdr5, Dclre1b, Fbl, Fgfr1, Flot1, Flot2, B4galt1, Gnb1, Gspt1, Hdac6, Herc2, Hsf1, Hsph1, Elavl1, Id2, Cyr61, Cep250, Insr, Eif3e
26344197	Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili	2015-09-17	AKT3, MED6, ABI1, GNPDA1, SRA1, TDRD15, HMGN1P30, PDCD6IP, PDCD6, MED16, ADA, CHAF1A, TOM1, RANBP9, SMC4, ARPC4-TTLL3, RBM14-RBM4, RNF103-CHMP3, CHURC1-FNTB, AP1M2, ISY1-RAB43, UBA2, SAE1, FARSB, DNM1L, ABCF2, COX17, SCAMP2, SCAMP3, DPP3, SNUPN, HUWE1, TSSC4, ATP9A, PQBP1, COL4A3BP, PTGES3L-AARSD1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR3, ACTR2, NUBP2, PPIF, LOC101060521, ARPC2, RAD50, ACTR1B, ACTR1A, ADAM8, LRPPRC, PDIA6, TRAP1, BCAP31, NAMPT, RBM12, G3BP1, ABI2, CEBPZ, TRIM28, AASS, ATP6AP2, WASF2, SLC25A13, CDK2, RBM7, ALYREF, TXNDC9, LOC101929876, PSME3, MPHOSPH10, MPHOSPH6, CDK5, NUTF2, EIF1, DDX39A, PSMD14, CDK7, PLIN3, HNRNPR, MRPS31, CDK8, RABEPK, RIDA, SRRM1, CDK9, STAM2, SF3B4, ZMPSTE24, AKAP8, STUB1, STAG1, UBE4B, PRSS16, SIGMAR1, BET1, CWC27, SAP18
23675907	Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients. Reprod. Biol. Endocrinol. Andriy Dorosh , Olina Tepla , Eva Zatecka , Lukas Ded , Karel Koci , Jana Peknicova	2013-01-01	GAPDHS, ACR, MND1, SPATA22
21832049	Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. J Biol Chem Judit OlÃ¡h , Orsolya Vincze , DezsÃµ VirÃ³k , DÃ³ra Simon , Zsolt BozsÃ³ , NatÃ¡lia TÃµkÃ©si , IstvÃ¡n HorvÃ¡th , Emma Hlavanda , JÃ¡nos KovÃ¡cs , Anna Magyar , MÃ¡ria SzÅ©cs , Ferenc Orosz , Botond Penke , Judit OvÃ¡di	2011-09-30	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20379614	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Mol. Med. Jed E Rose , FrÃ©dÃ©rique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl	2010-03-17	-
18187620	Identification of host proteins required for HIV infection through a functional genomic screen. Science Abraham L Brass , Derek M Dykxhoorn , Yair Benita , Nan Yan , Alan Engelman , Ramnik J Xavier , Judy Lieberman , Stephen J Elledge	2008-02-15	gag, gag-pol, vif, vpr, tat, rev, vpu, env, nef, MED6, PIGK, HUWE1, PDIA6, MPHOSPH6, ADAM10, RABEPK, RRAGB, ATG7, ARPC1A, POLR3F, LEFTY1, PNRC1, TMED2, PRDM7, POLR3A, ERI2, SLC46A1, SFT2D1, GABARAPL2, CARD16, PKD1L2, XKR4, AGAP2, AP2M1, CLN3, CLNS1A, ERP27, ANKRD9, ZNF720, RPTN, ARHGEF19, ZNF831, C4orf33, SOWAHA, C9orf131, RIMS4, FAM76B, ZNF785, LYPD4, PM20D1, IQUB, ZNF791, DDOST, DDX3X, DMXL1, DDX10, TIMM8A, DDX53, EDNRA, AGO3, EGF, EGFR, CRTC2, EPS8, ERCC3, AKT1, AKT2, ETF1, DOK6, C6orf1, LNX2, FHL3, COG2, TRAPPC8, ANKRD6, BAHD1, FBXO21, WDTC1, FLII, SEPT8, MDN1, OTUD3, SCFD1, NUP160, FBXW11, ARHGEF12, FNTA, PIP5K1C, PHF3, ETHE1, TNPO3, KLHDC2, MKRN2, COG4, TRIM58, INTS7, SPATS2L, GAPVD1, RSL1D1

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