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84023 Ptger4

84023

Ptger4

prostaglandin E receptor 4

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition prostaglandin E receptor 4

研究结论

Date Results Publications
2021-02-06 13:53:00 Role of the PGE2 receptor in ischemia-reperfusion injury of the rat retina. 32165825
2020-12-05 12:57:00 A representative metalloprotease induces PGE2 synthesis in fibroblast-like synoviocytes via the NF-kappaB/COX-2 pathway with amplification by IL-1beta and the EP4 receptor. 32094439
2020-01-18 12:10:00 This work has generated a set of novel homology models of the rEP4 and hEP4 receptors. 31455205
2018-06-02 10:41:00 We found that rats injected with the 30mug dose of PGE2 exhibited the most pronounced thermal nociceptive hypersensitivity though secondary analysis showed that rats injected with PGE2 doses of 0.03-30mug had lower withdrawal latencies as compared to rats injected with vehicle. 29031391
2017-06-24 11:17:00 Data suggest that EP4 recycling contributes to agonist-induced cell surface abundance and consequently enhanced receptor sensitivity. Facilitating EP4 externalization and recycling is a novel mechanism underlying PGE2-induced nociceptor sensitization. 27060485

名称对应

Type IDs
Synonymous EP4, Ptger, Ptgerep4
Gene
UniProtKB-ID: PE2R4_RAT, A0A0G2JSM6_RAT
UniprotKB: P43114, A0A0G2JSM6
UniParc: UPI000016827B, UPI000013153A
EMBL: AABR07072710, U94709, AC094562, CH474048, D28860
Ensembl: ENSRNOG00000013240
KO: rno:84023
Nucleutide sequences
EMBL-CDS: BAA06011.1, AAB53326.1, EDL75721.1
Gene_ORFName: rCG_51033
Ensembl_TRS: ENSRNOT00000017886
Protein sequencees
Ensembl_PRO: ENSRNOP00000017886
RefSeq: NP_114465.3, XP_006232058.1
Others
UniRef100: UniRef100_A0A0G2JSM6, UniRef100_P43114
UniRef90: UniRef90_P43114
UniRef50: UniRef50_P43114
UniGene: Rn.16062

全选

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研究热度

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