| Type | Description |
|---|---|
| Definition | insulin receptor substrate 3 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | 53BP2S interacts and modulates the insulin signals mediated by insulin receptor substrates. | 17965023 |
| 2010-01-21 00:00:00 | IRS-3 may play a unique role in mitogenesis by inhibiting insulin-stimulated cell cycle progression via a decrease in cyclin D1 and p21 expressions as well as suppression of c-myc mRNA induction | 15331570 |
| 2010-01-21 00:00:00 | Cyclic GMP-dependent protein kinase increases the DNA binding potential of C/EBPbeta by preventing the negative effects of GSK-3 phosphorylation | 16055922 |
| 2010-01-21 00:00:00 | IRS-3 expression blocked glucose/IGF-1 induced IRS-2 translocation from the cytosol to the plasma membrane, dampening IRS-2/IGF-1R interaction and subsequent activation of the PI3K/PKB/GSK3 signaling pathway | 12850284 |
| 2010-01-21 00:00:00 | These results suggest that intracellular localization of IRS-3 is determined by a different mechanism from other IRS proteins, and that IRS-3 possesses a transcription-regulating activity | 11724774 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
O08724_RAT,
B1WBQ1_RAT
UniprotKB:
O08724,
B1WBQ1
UniParc:
UPI00000E6B75,
UPI000019B60D
EMBL:
AC107410,
CH473973,
BC161840,
U93880
Ensembl:
ENSRNOG00000001389
KO:
rno:84021
|
| Nucleutide sequences |
EMBL-CDS:
AAC53161.1,
EDM13246.1,
AAI61840.1
Gene_ORFName:
rCG_21781
Ensembl_TRS:
ENSRNOT00000001874
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000001874
RefSeq:
NP_114463.1,
XP_017453954.1
|
| Others |
UniRef100:
UniRef100_B1WBQ1,
UniRef100_O08724
UniRef90:
UniRef90_B1WBQ1
UniRef50:
UniRef50_B1WBQ1
UniGene:
Rn.9791
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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