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83989 FAM172A

83989

FAM172A

family with sequence similarity 172 member A

protein-coding

Homo sapiens

基因描述

Type Description
Definition family with sequence similarity 172 member A

研究结论

Date Results Publications
2020-08-12 13:25:00 FAM172A recombinant protein could induce proliferation of HepG2 cells, in which the MAPK/ERK and PI3K/Akt signaling pathways might be involved. The role of FAM172A in HepG2 cell proliferation also indicated its possible involvement in hepatocellular carcinoma. 31915594
2018-03-03 12:04:00 our study showed that miR27a expression is a diagnostic and prognostic marker and correlates with overall survival of patients with CRC. Therefore, it may be a therapeutic approach for preventing metastasis of CRC to inhibit expression of miR27a or increase expression of FAM172A. 28440497
2017-07-08 12:44:00 Mesenchymal circulating tumor cells and FAM172A detection may predict highrisk stage II colorectal cancer. Our research proved that circulating tumor cells were feasible surrogate samples to detect gene expression and could serve as a predictive biomarker for tumor evaluation 28618931
2017-02-18 11:49:00 FAM172A might play a role in the carcinogenesis of CRC by inhibiting the growth and invasion of CRC cells. The mechanisms by which FAM172A exerts its function seem to involve activation of ERS signaling. 26637224
2016-10-29 11:58:00 Our results showed that FAM172A could suppress proliferation of colon cancer cells, and could bind to the minimum promoter region of FAM172A and upregulated the expression of FAM172A 26676844

名称对应

Type IDs
Synonymous C5orf21, Toupee
Gene
UniProtKB-ID: F172A_HUMAN, A0A024RAL9_HUMAN, B4DMI0_HUMAN
UniprotKB: Q8WUF8, A0A024RAL9, B4DMI0
UniParc: UPI00001B0222, UPI000006DF3B, UPI00017A7513, UPI00017A7097, UPI0000E0970D
EMBL: AL136630, AC117528, AK312930, AK297471, AC099501, AC108102, AK296986, AC093268, KF573671, CH471084, BC020584, AK295879, AC114980, AC106818
Ensembl: ENSG00000113391
KO: hsa:83989
Nucleutide sequences
EMBL-CDS: CAB66565.1, AAH20584.1, BAG59527.1, BAG58676.1, EAW96012.1, BAG35773.1, EAW96013.1, BAG59892.1
Gene_ORFName: hCG_2016229
Ensembl_TRS: ENST00000509163, ENST00000395965, ENST00000505869, ENST00000509739
Protein sequencees
Ensembl_PRO: ENSP00000426284, ENSP00000379294, ENSP00000423841, ENSP00000421834
RefSeq: XP_011541975.1, XP_016865445.1, XP_005272168.1, NP_001156890.1, XP_006714781.1, XP_005272167.1, XP_016865448.1, XP_006714780.1, XP_005272163.1, XP_011541974.1, XP_005272160.1, XP_011541972.1, XP_005272165.1, XP_016865443.1, XP_005272162.1, XP_016865450.1, NP_001156889.1, XP_016865447.1, XP_016865444.1, XP_011541970.1, XP_011541976.1, NP_114431.2, XP_016865451.1, XP_006714782.1, XP_016865442.1, XP_016865441.1, XP_011541973.1, XP_005272166.1, XP_016865449.1, XP_016865446.1
Others
UniRef100: UniRef100_Q8WUF8, UniRef100_B4DMI0
UniRef90: UniRef90_Q8WUF8, UniRef90_A0A2K5KKT2
UniRef50: UniRef50_Q8WUF8, UniRef50_Q8WUF8-2
UniGene: Hs.600086
CCDS: CCDS54880.1, CCDS4069.1, CCDS54879.1

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