| Type | Description |
|---|---|
| Definition | sphingolipid transporter 1 (putative) |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 10:11:00 | SPNS1-dependent L-leucine export across the lysosomal membrane is a key step for triggering autophagy, and that this mechanism is impaired in Niemann-Pick type C disease-1. | 29162837 |
| 2019-06-29 11:27:00 | Spindlin 1 (SPIN1) sequesters ribosomal protein uL18 in the nucleolus, preventing it from interacting with c-mdm2 protein (MDM2), and alleviating uL18-mediated inhibition of MDM2 ubiquitin ligase activity toward p53 tumor suppressor protein (p53). | 29547122 |
| 2013-01-26 10:21:00 | A single nucleotide polymorphism located within the spns1 gene is associated with plasma triglyceride levels. | 22942098 |
| 2005-04-21 21:00:00 | Spinster protein interferes with programmed cell death in Drosophila melanogaster and has orthologs in nematode, mouse, and human. | 11340170 |
| Type | IDs |
|---|---|
| Synonymous | HSpin1, LAT, PP2030, SPIN1, SPINL, nrs |
| Gene |
UniProtKB-ID:
SPNS1_HUMAN,
A0A024QZ93_HUMAN
UniprotKB:
Q9H2V7,
A0A024QZ93
UniParc:
UPI000059D352,
UPI00000728A3,
UPI000000DC4A,
UPI0000037C3A,
UPI000004DB99
EMBL:
BC006156,
BC047741,
AK289787,
BC038961,
AK095677,
AL390215,
BC065235,
AC109460,
BC008325,
AF212371,
CH471267,
AF370423
Ensembl:
ENSG00000169682
KO:
hsa:83985
|
| Nucleutide sequences |
EMBL-CDS:
AAH38961.1,
CAB99229.1,
EAW52018.1,
AAH08325.1,
AAH47741.1,
BAC04603.1,
AAH06156.1,
BAF82476.1,
AAH65235.1,
EAW52019.1,
AAQ15259.1,
AAG43830.1,
EAW52022.1,
EAW52023.1,
EAW52021.1
Gene_ORFName:
PP20300,
hCG_2002366
Ensembl_TRS:
ENST00000352260,
ENST00000323081,
ENST00000334536,
ENST00000311008
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000309945,
ENSP00000335494,
ENSP00000318228,
ENSP00000306050
RefSeq:
NP_001135922.1,
XP_006721159.1,
NP_001135921.1,
XP_024306236.1,
NP_114427.1,
NP_001135923.1,
NP_001135920.1,
XP_024306235.1,
XP_016879247.1,
XP_016879246.1
|
| Others |
UniRef100:
UniRef100_Q9H2V7
UniRef90:
UniRef90_Q9H2V7
UniRef50:
UniRef50_Q9H2V7
UniGene:
Hs.617449
CCDS:
CCDS10646.1,
CCDS45453.1,
CCDS45454.1,
CCDS45452.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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