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8396 PIP4K2B

8396

PIP4K2B

phosphatidylinositol-5-phosphate 4-kinase type 2 beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphatidylinositol-5-phosphate 4-kinase type 2 beta

研究结论

Date Results Publications
2020-07-04 10:58:00 the loss of PIP4Ks (PIP4K2A, PIP4K2B, and PIP4K2C) in vitro results in a paradoxical increase in PI(4,5)P2 and a concomitant increase in insulin-stimulated production of PI(3,4,5)P3. 31091439
2020-02-01 11:44:00 MiR-3064, a key oncogenic miRNA, could promote PC cell growth, invasion and sphere formation via downregulating the levels of tumor suppressor PIP4K2B. 31488171
2017-08-05 11:44:00 PIP4K2B couples the cellular GTP concentration to the levels of the stress-regulated phosphoinositide PtdIns5P, to impact on tumor cell growth. 27132569
2015-08-29 10:53:00 Suppression of PIP4K expression selectively prevents tumor cell growth in vitro and prevents tumor development in mice that have lost the tumor suppressor p53. (Review) 25728392
2014-03-01 11:50:00 Association between low PIP4K2B expression and poor patient survival.Analysis of gene expression datasets confirmed the association between low PIP4K2B and low CDH1expression. 24127122

名称对应

Type IDs
Synonymous PI5P4KB, PIP5K2B, PIP5KIIB, PIP5KIIbeta, PIP5P4KB
Gene
UniProtKB-ID: PI42B_HUMAN
UniprotKB: P78356
UniParc: UPI0000032D92, UPI0000071F0F
EMBL: BC027459, BT019614, U85245
Ensembl: ENSG00000277292, ENSG00000276293
KO: hsa:8396
Nucleutide sequences
EMBL-CDS: AAH27459.1, AAV38420.1, AAB48596.1
Ensembl_TRS: ENST00000613180, ENST00000619039
Protein sequencees
Ensembl_PRO: ENSP00000480776, ENSP00000482548
RefSeq: XP_011523628.1, XP_016880688.1, XP_011523632.1, XP_016880686.1, XP_011523629.1, NP_003550.1
Others
UniRef100: UniRef100_P78356
UniRef90: UniRef90_P78356
UniRef50: UniRef50_P78356
UniGene: Hs.260603
CCDS: CCDS11329.1

全选

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