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8395 PIP5K1B

8395

PIP5K1B

phosphatidylinositol-4-phosphate 5-kinase type 1 beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphatidylinositol-4-phosphate 5-kinase type 1 beta

研究结论

Date Results Publications
2015-08-29 10:47:00 Data indicate that type I phosphatidylinositol 4-phosphate 5-kinase PIP5KIbeta mutants whose dimerization was impaired showed a severe decrease in PI(4,5)P2 production and plasma membrane delocalization. 25713054
2014-03-29 11:51:00 Knockdown of PIP5K1B in fibroblasts reproduced abnormal actin cytoskeleton remodeling evidenced in Friedreich's ataxia patient cells. 23552101
2010-10-23 10:13:00 Results identify PIPKIbeta as a novel regulator of focal adhesion disassembly and suggest that PIPKIbeta spatially regulates beta1 integrin endocytosis at adhesion sites to control cell migration. 20624912
2010-09-27 12:41:00 Results identify an isoform-specific PDZ-binding motif in PIP5KIbeta, which confers specificity for PIP5KIbeta signaling at the uropod during leukocyte chemotaxis. 20442317
2010-06-30 22:06:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614

名称对应

Type IDs
Synonymous MSS4, STM7
Gene
UniProtKB-ID: PI51B_HUMAN, Q7KYT6_HUMAN
UniprotKB: O14986, Q7KYT6
UniParc: UPI0000210ACD, UPI000016B23F, UPI000013D612, UPI000002E327
EMBL: AK292734, CH471089, X92493, U52387, AL356219, U78579, U52381, U52378, U52376, U52379, U52386, U78580, U52384, U52382, U52380, U52385, AL354794, AL162730, AK295587, BC030587, U52383, U52377
Ensembl: ENSG00000107242
KO: hsa:8395
Nucleutide sequences
EMBL-CDS: EAW62465.1, CAA63224.1, BAF85423.1, AAC50915.1, BAG58479.1, AAH30587.1, AAC51327.1, AAC50914.1
Ensembl_TRS: ENST00000265382, ENST00000478500, ENST00000541509
Protein sequencees
Ensembl_PRO: ENSP00000438082, ENSP00000265382, ENSP00000435778
RefSeq: NP_003549.1, NP_001362970.1, NP_001362966.1, NP_001362969.1, XP_011517386.1, NP_001265182.1, NP_001362968.1, NP_001362965.1, XP_016870678.1, XP_011517384.1, XP_005252319.1, XP_011517385.1, XP_016870677.1
Others
UniRef100: UniRef100_O14986
UniRef90: UniRef90_O14986
UniRef50: UniRef50_O70161-2
UniGene: Hs.534371
CCDS: CCDS6624.1, CCDS65063.1

全选

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