| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 2A |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:35:00 | Translation Regulation by eIF2alpha Phosphorylation and mTORC1 Signaling Pathways in Non-Communicable Diseases (NCDs). | 32722591 |
| 2020-09-12 16:05:00 | miR195 promotes LPSmediated intestinal epithelial cell apoptosis via targeting SIRT1/eIF2a. | 31894250 |
| 2020-08-01 13:48:00 | This review summarizes the canonical roles of each branch of the integrated stress response (ISR_ and follow up with consideration and evidence of their implications in neurodegenerative pathologies. The maladaptive outcomes of ISR kinase activation and eIF2alpha phosphorylation, which might play mechanistic roles in neurodegeneration were also examined. [Review] | 31913484 |
| 2020-05-02 12:31:00 | GADD45alpha is a key mediator of ER stress-induced growth arrest via regulation of the G2/M transition and cell death through the eIF2alpha signaling pathway. | 31847234 |
| 2020-02-22 12:07:00 | A MYC-GCN2-eIF2alpha negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer. | 31685988 |
| Type | IDs |
|---|---|
| Synonymous | CDA02, EIF-2A, MST089, MSTP004, MSTP089 |
| Gene |
UniProtKB-ID:
EIF2A_HUMAN,
F8WAE5_HUMAN
UniprotKB:
Q9BY44,
F8WAE5
UniParc:
UPI00017A7899,
UPI00014F7ACE,
UPI00000473DB,
UPI00017A6DD4,
UPI0001B79733
EMBL:
AK293993,
AC107426,
CH471052,
AF212241,
AF172818,
AK027356,
AF109358,
BC011885,
AF497978,
AK298586
Ensembl:
ENSG00000144895
KO:
hsa:83939
|
| Nucleutide sequences |
EMBL-CDS:
EAW78831.1,
AAK14926.1,
AAM83402.1,
BAG60776.1,
AAH11885.1,
BAB55058.1,
AAQ13612.1,
BAG57357.1,
AAQ13506.1,
EAW78830.1
Gene_ORFName:
MSTP004,
CDA02,
MSTP089
Ensembl_TRS:
ENST00000460851,
ENST00000487799,
ENST00000406576,
ENST00000273435
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000417229,
ENSP00000420537,
ENSP00000385292,
ENSP00000273435
RefSeq:
NP_114414.2,
NP_001305972.1,
NP_001305973.1,
XP_024309555.1,
NP_001305975.1,
NP_001305974.1,
XP_011511526.1
|
| Others |
UniRef100:
UniRef100_F8WAE5,
UniRef100_Q9BY44
UniRef90:
UniRef90_Q9BY44
UniRef50:
UniRef50_Q9BY44
UniGene:
Hs.655782
CCDS:
CCDS82861.1,
CCDS46935.1,
CCDS82859.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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