| Type | Description |
|---|---|
| Definition | transcriptional repressor GATA binding 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:08:00 | Study characterized the murine Wnt5a promoter and showed that two alternative Wnt5a transcripts, Ts1 and Ts2, are differentially expressed in the developing skeletal elements. Ts2 expression decreases while Ts1 expression increases during chondrocyte differentiation. The transcription factor Trps1 and the activator form of Gli3 (Gli3A), which is a mediator of Hedgehog signaling, activate Wnt5a expression. | 31550480 |
| 2020-05-09 12:26:00 | These results demonstrated that TRPS1 plays indispensable roles during mouse zygotic genome activation through controlling the expression of zygotic genome activation markers MuERV-L and Zscan4d, transcription factors SOX2 and OCT4, and key histone markers H3K4me3 and H3K27me3. | 30712485 |
| 2020-02-15 13:01:00 | TRPS1 can function as a context-dependent tumor suppressor in breast cancer, while being essential for growth and differentiation of normal mammary epithelial cells. | 31879358 |
| 2019-11-09 11:25:00 | This study has demonstrated that Trps1 is a positive regulator of cell proliferation in both dental mesenchyme and epithelium, suggesting that the microdontia in trichorhinophalangeal syndrome is likely due to decreased cell proliferation in developing tooth organs. | 30691926 |
| 2017-02-04 11:21:00 | our findings partially explain why patients with TRPS show a broad range of congenital cardiac defects, although Trps1 expression is observed in a more restricted fashion. | 27257806 |
| Type | IDs |
|---|---|
| Synonymous | AI115454, AI447310, D15Ertd586e |
| Gene |
UniProtKB-ID:
V9GX74_MOUSE,
Q3UQJ9_MOUSE,
G3UW90_MOUSE,
V9GXE9_MOUSE
UniprotKB:
V9GX74,
Q3UQJ9,
G3UW90,
V9GXE9
UniParc:
UPI0000D62FE3,
UPI0003B9299F,
UPI00002154E0,
UPI00005AC126
EMBL:
AK142355,
AC112158,
AC155307,
AC142245
Ensembl:
ENSMUSG00000038679
KO:
mmu:83925
|
| Nucleutide sequences |
EMBL-CDS:
BAE25041.1
Ensembl_TRS:
ENSMUST00000183757,
ENSMUST00000165201,
ENSMUST00000077935,
ENSMUST00000183997
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000139017,
ENSMUSP00000129779,
ENSMUSP00000077089,
ENSMUSP00000139115
RefSeq:
XP_030104686.1,
XP_011244078.1,
XP_036015545.1,
NP_001297414.1,
XP_011244079.1,
XP_011244080.1,
XP_006521626.1,
XP_036015539.1,
XP_036015541.1,
XP_036015542.1,
NP_114389.2,
XP_036015546.1,
XP_006521623.1,
XP_030104688.1,
XP_011244082.1,
XP_036015544.1,
XP_036015540.1,
NP_001297410.1,
XP_036015538.1,
XP_036015543.1
|
| Others |
UniRef100:
UniRef100_V9GXE9,
UniRef100_V9GX74,
UniRef100_Q3UQJ9
UniRef90:
UniRef90_Q9UHF7,
UniRef90_V9GXE9
UniRef50:
UniRef50_Q9UHF7
UniGene:
Mm.30466
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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