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83892 KCTD10

83892

KCTD10

potassium channel tetramerization domain containing 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition potassium channel tetramerization domain containing 10

研究结论

Date Results Publications
2020-06-06 12:02:00 EIF3D is a novel substrate of CUL3/KCTD10 ubiquitin ligase. The ubiquitin code of EIF3D is K27-polyubiquitination at the lysine 153 and 275 residues. 31280863
2020-02-22 12:29:00 The study showed that ERCC6 and HTRA1single nucleotide polymorphisms rs3793784 and rs11200638 were associated with increased odds of early and exudative age-related macular degeneration, while the variant in KCTD10 (rs56209061) was found to be protective. 31583032
2019-11-02 10:52:00 results suggest that CEP97 degradation by the cullin-3-RBX1-KCTD10 complex plays a crucial role in serum-starvation-induced CP110 removal and ciliogenesis 30404837
2019-02-23 10:41:00 identified the RING E3 ligase complex Cullin-3-Rbx1-KCTD10 as key modulator of endothelial barrier integrity via its regulation of the ubiquitination, localization, and activity of RhoB. 29358211
2019-02-16 11:15:00 This novel molecular axis (CUL3/KCTD10/RhoB) positively regulates the activity of Rac1 in HER2-positive breast cancers. 30515933

名称对应

Type IDs
Synonymous BTBD28, MSTP028, ULRO61, hBACURD3
Gene
UniProtKB-ID: BACD3_HUMAN, A0A024RBJ2_HUMAN
UniprotKB: Q9H3F6, A0A024RBJ2
UniParc: UPI0000DAC990, UPI0000DAC991, UPI000004DAE1
EMBL: AY205299, AB209358, AY597809, BC040062, AC007570, AK222548, CH471054, AF113208, AK027543
Ensembl: ENSG00000110906
KO: hsa:83892
Nucleutide sequences
EMBL-CDS: BAD92595.1, AAH40062.1, BAD96268.1, AAG39279.1, AAT09002.1, AAO47716.1, BAB55188.1, EAW97862.1, EAW97861.1
Gene_ORFName: MSTP028, hCG_40324
Ensembl_TRS: ENST00000228495
Protein sequencees
Ensembl_PRO: ENSP00000228495
RefSeq: NP_114160.1, NP_001304324.1, NP_001304328.1
Others
UniRef100: UniRef100_Q9H3F6
UniRef90: UniRef90_Q9H3F6
UniRef50: UniRef50_Q9H3F6
UniGene: Hs.524731
CCDS: CCDS9128.1

全选

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