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83874 TBC1D10A

83874

TBC1D10A

TBC1 domain family member 10A

protein-coding

Homo sapiens

基因描述

Type Description
Definition TBC1 domain family member 10A

研究结论

Date Results Publications
2020-10-31 13:14:00 Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins. 31527750
2017-08-05 10:32:00 Data suggest that Rab35, interacting with TBC1D10A, functions in vascular endothelial cells as a negative regulator of histamine-evoked, Ca2+-dependent Weibel-Palade body exocytosis, most likely acting through the downstream effectors ACAP2 and Arf6. (Rab35 = rab GTP-binding protein 53; TBC1D10A = TBC1 domain family member 10A; ACAP2 = centaurin beta2; Arf6 = ADP-ribosylation factor 6) 28566286
2014-12-20 11:11:00 EPI64, a candidate GAP that is specific for Rab27. 24673604
2013-08-31 10:14:00 Data suggest that EPI64A and B, which are ubiquitously expressed members of the EPI64 subfamily, inactivate Ras and certain Rabs at the periphery of cells. 23248241
2012-07-28 10:21:00 EPI64 regulates membrane trafficking both by stabilizing Arf6-GTP and by inhibiting the recycling of membrane through the tubular endosome by decreasing Rab8a-GTP levels. 22219378

名称对应

Type IDs
Synonymous EPI64, TBC1D10, dJ130H16.1, dJ130H16.2
Gene
UniProtKB-ID: TB10A_HUMAN, B7ZVY9_HUMAN, A7E244_HUMAN
UniprotKB: Q9BXI6, B7ZVY9, A7E244
UniParc: UPI000189A9AF, UPI000022B7BB, UPI0000001BE4, UPI000158A28A
EMBL: AK074656, AC004997, AB449894, AF331038, BC171775, BC150214, BC136815, AK127939, BC150187, BC142940, CT841514, CH471095
Ensembl: ENSG00000099992
KO: hsa:83874
Nucleutide sequences
EMBL-CDS: EAW59876.1, AAI50215.1, BAC11117.1, BAG54600.1, AAC23434.1, AAI42941.1, AAI36816.1, AAK35048.1, BAH16637.1, EAW59874.1, CAJ86444.1, AAI71775.1, AAI50188.1
Ensembl_TRS: ENST00000403477, ENST00000215790
Protein sequencees
Ensembl_PRO: ENSP00000384996, ENSP00000215790
RefSeq: NP_001191169.1, NP_114143.1
Others
UniRef100: UniRef100_A7E244, UniRef100_Q9BXI6, UniRef100_B7ZVY9
UniRef90: UniRef90_Q9BXI6
UniRef50: UniRef50_Q9BXI6
UniGene: Hs.655273
CCDS: CCDS56227.1, CCDS13874.1

全选

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