| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 26 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 10:57:00 | These results represent the first in vivo evidence showing that USP26 is not essential for mouse gametogenesis. | 30887115 |
| 2018-01-27 12:08:00 | findings demonstrate TGF-beta enhances expression of USP26 and reinforces SMAD7 stability by limiting the ubiquitin-mediated turnover of SMAD7; clinically, loss of USP26 correlates with high TGF-beta activity and confers poor prognosis in glioblastoma; data identify USP26 as a novel negative regulator of the TGF-beta pathway and suggest that loss of USP26 expression may be an important factor in glioblastoma pathogenesis | 28381482 |
| 2017-12-09 11:12:00 | Data show that USP26 interacts with PRC1 components chromobox (CBX)-containing proteins CBX4 and CBX6. | 28839133 |
| 2017-09-30 12:00:00 | A novel USP26 variant p.R344W is associated with nonobstructive azoospermia probably through affecting androgen receptor function. | 27089915 |
| 2017-06-03 11:36:00 | The interaction between USP26 and Mdm2, and the subsequent deubiquitination of Mdm2, serves, most probably to regulate Mdm2. Future therapeutic modalities that interfere with the association between USP26 and Mdm2 will be used to destabilize the ligase in malignancies where it is upregulated. | 27810359 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UBP26_HUMAN
UniprotKB:
Q9BXU7
UniParc:
UPI00000421FD
EMBL:
Z81365,
BC101191,
BC069073,
BC101190,
AF285593
Ensembl:
ENSG00000134588
KO:
hsa:83844
|
| Nucleutide sequences |
EMBL-CDS:
AAK31972.1,
AAI01191.1,
AAH69073.1,
AAI01192.1
Ensembl_TRS:
ENST00000370832,
ENST00000511190
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000423390,
ENSP00000359869
RefSeq:
NP_114113.1,
XP_016885381.1
|
| Others |
UniRef100:
UniRef100_Q9BXU7
UniRef90:
UniRef90_Q9BXU7
UniRef50:
UniRef50_Q9BXU7
UniGene:
Hs.333137
CCDS:
CCDS14635.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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