| Type | Description |
|---|---|
| Definition | mitotic arrest deficient 1 like 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:08:00 | Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint. | 32202322 |
| 2021-03-20 13:29:00 | Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint. | 32236513 |
| 2020-10-24 14:02:00 | Association of MAD1L1 polymorphism (rs871925) with prenatal famine exposure and schizophrenia in a Chinese population: A case-control study. | 31498969 |
| 2020-05-23 11:38:00 | We identified and replicated three new genome-wide significant signals of association with idiopathic pulmonary fibrosis susceptibility (associated with altered gene expression of KIF15, MAD1L1, and DEPTOR). New signals of association implicating KIF15 and MAD1L1 suggest a possible role of mitotic spindle-assembly genes in IPF susceptibility. | 31710517 |
| 2020-04-18 12:40:00 | MAD1-dependent pool of CDK1-CCNB1 creates a positive feedback loop necessary for timely recruitment of MPS1 to kinetochores during mitotic entry and for sustained spindle checkpoint arrest. CDK1-CCNB1 is therefore an integral component of the spindle checkpoint, ensuring the fidelity of mitosis. | 30674583 |
| Type | IDs |
|---|---|
| Synonymous | MAD1, PIG9, TP53I9, TXBP181 |
| Gene |
UniProtKB-ID:
MD1L1_HUMAN
UniprotKB:
Q9Y6D9
UniParc:
UPI0000072C4D,
UPI00003E282E
EMBL:
BC009964,
AC006433,
AC104129,
AC110781,
AF083811,
AK090959,
U33822,
AC005282,
AF123318,
AC069288
Ensembl:
ENSG00000002822
KO:
hsa:8379
|
| Nucleutide sequences |
EMBL-CDS:
AAP21876.1,
AAD20359.1,
BAG52253.1,
AAH09964.1,
AAD24498.1,
AAC52059.1,
AAS07503.1
Ensembl_TRS:
ENST00000399654,
ENST00000406869,
ENST00000402746,
ENST00000265854
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265854,
ENSP00000384155,
ENSP00000382562,
ENSP00000385334
RefSeq:
NP_001013858.1,
NP_001291453.1,
NP_001291452.1,
NP_001013859.1,
NP_001291454.1,
NP_003541.2
|
| Others |
UniRef100:
UniRef100_Q9Y6D9
UniRef90:
UniRef90_Q9Y6D9
UniRef50:
UniRef50_Q9Y6D9
UniGene:
Hs.654838
CCDS:
CCDS43539.1,
CCDS78201.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员