| Type | Description |
|---|---|
| Definition | FERM domain containing 8 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 12:13:00 | FRMD8 promotes inflammatory and growth factor signaling by stabilizing the iRhom2/ADAM17 sheddase complex. | 29897336 |
| 2019-04-20 12:13:00 | iTAP (FRMD8) is a novel iRhom2 interactor that controls TNF-alpha secretion by policing the stability of iRhom2/ADAM17 complex. | 29897333 |
| Type | IDs |
|---|---|
| Synonymous | FKSG44, iTAP |
| Gene |
UniProtKB-ID:
FRMD8_HUMAN,
A8K6L3_HUMAN
UniprotKB:
Q9BZ67,
A8K6L3
UniParc:
UPI00015DA854,
UPI000006D98D,
UPI00001FAB85,
UPI000000DAAC
EMBL:
AK291678,
BC044658,
AK074850,
AK304363,
AP000944,
BC051695,
AF334946
Ensembl:
ENSG00000126391
KO:
hsa:83786
|
| Nucleutide sequences |
EMBL-CDS:
BAC11244.1,
AAG50295.1,
AAH51695.1,
AAH44658.1,
BAG65203.1,
BAF84367.1
Gene_ORFName:
FKSG44
Ensembl_TRS:
ENST00000416776,
ENST00000317568,
ENST00000355991
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348270,
ENSP00000392111,
ENSP00000319726
RefSeq:
NP_114110.1,
NP_001287761.1,
NP_001287762.1
|
| Others |
UniRef100:
UniRef100_A8K6L3,
UniRef100_Q9BZ67
UniRef90:
UniRef90_Q9BZ67
UniRef50:
UniRef50_Q9BZ67
UniGene:
Hs.578433
CCDS:
CCDS76432.1,
CCDS73320.1,
CCDS8102.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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