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83771 Tas1r3

83771

Tas1r3

taste receptor, type 1, member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition taste receptor, type 1, member 3

研究结论

Date Results Publications
2020-09-19 16:27:00 Allelic variation of the Tas1r3 taste receptor gene affects sweet taste responsiveness and metabolism of glucose in F1 mouse hybrids. 32673349
2020-05-16 12:31:00 TAS1R3 is not required to mount an immune response to the helminth Heligmosomoides polygyrus, which infects the proximal small intestine. Examination of uninfected Tas1r3(-/-) mice revealed a modest reduction in the number of tuft cells in the proximal small intestine but a severe decrease in the distal small intestine at homeostasis. 31980480
2019-05-25 12:37:00 this study shows that taste receptor T1R3 promotes the tumoricidal activity of hepatic CD49a(+) CD49b(-) natural killer cells 30259960
2019-01-05 11:28:00 residual sensitivity by the T1R1+T1R3 KO mice demonstrates that a T1R-independent mechanism can contribute to the detectability of high concentrations of this prototypical umami compound stimulus 29443544
2018-12-22 10:15:00 Data suggest that Tas1r2 and Tas1r3 are involved in regulation of Glp1 secretion in enteroendocrine cells; 3DG (3-deoxyglucosone) attenuates high glucose-stimulated Glp1 secretion by antagonizing Tas1r2/Tas1r3 subunits and downstream cAMP signaling. (Tas1r2 = sweet taste receptor subunit Tas1r2; Tas1r3 = sweet taste receptor subunit Tas1r3; Glp1 = glucagon-like peptide-1) 29277113

名称对应

Type IDs
Synonymous Sac, T1r3
Gene
UniProtKB-ID: TS1R3_MOUSE
UniprotKB: Q925D8
UniParc: UPI00000230BB
EMBL: AF337039, AB049994, AF368024, AL670236, AY026318, AY032621, AB055708, AF368025, AF311386
Ensembl: ENSMUSG00000029072
KO: mmu:83771
Nucleutide sequences
EMBL-CDS: AAK01937.1, BAB62852.1, AAK39436.1, AAK51602.1, AAK55536.1, BAB47181.1, AAK55537.1, AAL08425.1
Ensembl_TRS: ENSMUST00000030949
Protein sequencees
Ensembl_PRO: ENSMUSP00000030949
RefSeq: NP_114078.1
Others
UniRef100: UniRef100_Q925D8
UniRef90: UniRef90_Q925D8
UniRef50: UniRef50_Q925D8
UniGene: Mm.358792
CCDS: CCDS19046.1

全选

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