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83746 L3MBTL2

83746

L3MBTL2

L3MBTL histone methyl-lysine binding protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition L3MBTL histone methyl-lysine binding protein 2

研究结论

Date Results Publications
2019-04-20 11:49:00 L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage, regulating the DNA damage response pathway. 29581593
2017-09-09 12:29:00 L3MBTL2 polymorphism is associated with neuroticism. 27918536
2011-08-06 11:13:00 Our findings highlight a PcG/L3MBTL2 collaboration that attains repressive chromatin without entailing histone lysine methylation marks. 21596310
2010-01-21 00:00:00 determination of the solution structure of the FCS zinc finger of L3MBTL2; structure consists of a beta-hairpin followed by an alpha-helix; structure is consistent with the proposal that FCS zinc fingers bind to regulatory RNAs 19241375
2010-01-21 00:00:00 High-resolution crystallographic analysis of the four MBT repeats of L3MBTL2 reveals its unique asymmetric rhomboid architecture, as well as binding mechanism, which preclude the interaction of the first three MBT repeats with methylated peptides. 19233876

名称对应

Type IDs
Synonymous H-l(3)mbt-l, L3MBT
Gene
UniProtKB-ID: LMBL2_HUMAN, A0A0S2Z5X6_HUMAN
UniprotKB: Q969R5, A0A0S2Z5X6
UniParc: UPI000002AD53, UPI000012E77E, UPI000002AD54
EMBL: KU178799, AL035658, AL136564, AJ305226, AK097052, AK074091, CR456482, AJ305227, AL035681, CH471095, BC017191
Ensembl: ENSG00000100395
KO: hsa:83746
Nucleutide sequences
EMBL-CDS: CAG30368.1, CAC37794.1, BAB84917.1, CAC37795.1, AAH17191.1, BAC04936.1, CAB66499.2, EAW60414.1, ALQ34257.1
Gene_ORFName: hCG_41118
Ensembl_TRS: ENST00000216237, ENST00000452106
Protein sequencees
Ensembl_PRO: ENSP00000216237, ENSP00000414423
RefSeq: XP_016884465.1, XP_024308047.1, XP_016884468.1, XP_016884467.1, NP_113676.2, XP_016884469.1, XP_011528723.1, XP_016884466.1, XP_011528722.1
Others
UniRef100: UniRef100_Q969R5
UniRef90: UniRef90_Q969R5
UniRef50: UniRef50_Q969R5
UniGene: Hs.517641
CCDS: CCDS14011.1

全选

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