| Type | Description |
|---|---|
| Definition | glutamate rich WD repeat containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:13:00 | GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway. | 31891681 |
| 2020-03-28 12:01:00 | findings suggest a novel oncogenic function of GRWD1 as a transcriptional regulator of p53 and that GRWD1 might be an attractive therapeutic target and prognostic marker in cancer therapy | 31545368 |
| 2017-08-19 11:36:00 | GRWD1 overexpression in combination with HPV16 E7 and activated KRAS confers anchorage-independent growth and tumorigenic capacity on normal human fibroblasts. Consistent with this, GRWD1 overexpression is associated with poor prognosis in cancer patients. | 27856536 |
| 2017-07-01 10:56:00 | Cdt1-binding protein GRWD1 promotes chromatin fluidity by influencing nucleosome structures, e.g., by transient eviction of H2A-H2B, and thereby promotes efficient MCM loading at replication origins. | 27552915 |
| Type | IDs |
|---|---|
| Synonymous | CDW4, GRWD, RRB1, WDR28 |
| Gene |
UniProtKB-ID:
GRWD1_HUMAN
UniprotKB:
Q9BQ67
UniParc:
UPI000012BB5B
EMBL:
EF011614,
AC008403,
BC002440,
AB075822,
AF337808,
CH471177
Ensembl:
ENSG00000105447
KO:
hsa:83743
|
| Nucleutide sequences |
EMBL-CDS:
EAW52347.1,
BAB85528.1,
ABK41104.1,
AAK17998.1,
AAH02440.1
Ensembl_TRS:
ENST00000253237
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000253237
RefSeq:
NP_113673.3
|
| Others |
UniRef100:
UniRef100_Q9BQ67
UniRef90:
UniRef90_Q9BQ67
UniRef50:
UniRef50_Q9BQ67
UniGene:
Hs.400625
CCDS:
CCDS12720.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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