| Type | Description |
|---|---|
| Definition | MARVEL domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-09 11:26:00 | MARVELD1 may regulate tumor cell proliferation and sensitivity to chemotherapeutic drugs via reducing the exorbitant reactive oxygen species. The mechanism was that MARVELD1 interacted with catalase to maintain latter stability, and then ensure continuous reactive oxygen species scavenge. | 31066116 |
| 2017-10-14 11:11:00 | MARVELD1 substantially inhibits nonsense-mediated RNA decay by decreasing the pioneer round of translation but not steady-state translation, and is an important component of the molecular machinery containing UPF1 and Y14. MARVELD1 promotes the dissociation of SMG1 from UPF1, resulting in the repression of serine phosphorylation of UPF1, and subsequently blocks the recruitment of SMG5. | 23826386 |
| 2017-05-20 12:02:00 | Study demonstrates that MARVELD1-mediated balance of integrin beta1 and beta4 regulates cell surface ultrastructure and epithelial-mesenchymal transition phenotype of non-small cell lung cancer (NSCLC). | 26509557 |
| 2015-10-03 10:56:00 | MARVELD1 silencing is an appealing diagnostic biomarker for lung cancer. | 25520033 |
| 2015-08-15 10:05:00 | Importin-beta1 mediates the non-classical nucleocytoplasmic transport of MARVELD1. | 26107903 |
| Type | IDs |
|---|---|
| Synonymous | GB14, MARVD1, MRVLDC1, bA548K23.8 |
| Gene |
UniProtKB-ID:
MALD1_HUMAN
UniprotKB:
Q9BSK0
UniParc:
UPI000006FAD7
EMBL:
BC062544,
BC004995,
AL355315
Ensembl:
ENSG00000155254
KO:
hsa:83742
|
| Nucleutide sequences |
Ensembl_TRS:
ENST00000285605
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000441365
RefSeq:
NP_113672.1
|
| Others |
UniRef100:
UniRef100_Q9BSK0
UniRef90:
UniRef90_Q9BSK0
UniRef50:
UniRef50_Q9BSK0
UniGene:
Hs.744073
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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