| Type | Description |
|---|---|
| Definition | itchy E3 ubiquitin protein ligase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:22:00 | Effects of CircRNA-ITCH on proliferation and apoptosis of hepatocellular carcinoma cells through inhibiting Wnt/beta-catenin signaling pathway. | 32862578 |
| 2020-12-05 13:02:00 | CircRNA ITCH increases bortezomib sensitivity through regulating the miR-615-3p/PRKCD axis in multiple myeloma. | 33031827 |
| 2020-12-05 13:01:00 | NORE1A directs apoptotic switch of TNF signaling through reciprocal modulation of ITCH-mediated destruction of TNFRI and BAX. | 32690868 |
| 2020-11-21 13:16:00 | Silencing E3 Ubiqutin ligase ITCH as a potential therapy to enhance chemotherapy efficacy in p53 mutant neuroblastoma cells. | 31974512 |
| 2020-10-03 12:55:00 | E3 Ligase ITCH Interacts with the Z Matrix Protein of Lassa and Mopeia Viruses and Is Required for the Release of Infectious Particles. | 31906112 |
| Type | IDs |
|---|---|
| Synonymous | ADMFD, AIF4, AIP4, NAPP1 |
| Gene |
UniProtKB-ID:
ITCH_HUMAN,
A0A590UJQ1_HUMAN
UniprotKB:
Q96J02,
A0A590UJQ1
UniParc:
UPI00000731C2,
UPI000007199B,
UPI0007DC77A7,
UPI00004AE2D2
EMBL:
AL356299,
AB056663,
AK304090,
AL109923,
AF095745,
CH471077,
BC011571,
BC006848,
AK315212,
AF038564,
KF511301,
AL136173,
KF511300
Ensembl:
ENSG00000078747
KO:
hsa:83737
|
| Nucleutide sequences |
EMBL-CDS:
BAB39389.1,
AAK39399.1,
AAC04845.1,
AAH06848.1,
EAW76276.1,
AAH11571.1,
BAG64996.1,
EAW76274.1,
BAG37647.1,
EAW76272.1
Ensembl_TRS:
ENST00000262650,
ENST00000665346,
ENST00000535650,
ENST00000374864,
ENST00000670516
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363998,
ENSP00000499786,
ENSP00000262650,
ENSP00000445608,
ENSP00000499526
RefSeq:
XP_016883578.1,
NP_001244066.1,
NP_113671.3,
NP_001244067.1,
XP_005260627.1,
XP_024307773.1,
XP_011527381.1,
XP_016883581.1,
NP_001311126.1,
XP_016883579.1,
NP_001311127.1,
XP_016883580.1
|
| Others |
UniRef100:
UniRef100_A0A590UJQ1,
UniRef100_Q96J02
UniRef90:
UniRef90_Q96J02,
UniRef90_P62627
UniRef50:
UniRef50_Q96J02
UniGene:
Hs.632272
CCDS:
CCDS58768.1,
CCDS58769.1,
CCDS13234.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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