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83732 RIOK1

83732

RIOK1

RIO kinase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition RIO kinase 1

研究结论

Date Results Publications
2019-08-10 11:47:00 Together, this study highlights the importance of a RIOK1 methylation-phosphorylation switch in determining colorectal and gastric cancer development. 29384474
2018-03-31 10:55:00 we demonstrate that RIOK1 promotes lung colonization in vivo and that RIOK1 is overexpressed in different subtypes of human lung- and breast cancer. 28499923
2017-02-18 10:17:00 Docking studies revealed that TIBI can occupy the ATP-binding site of Rio1 in a manner similar to toyocamycin, and enhances the thermostability of the enzyme. 27909846
2017-01-14 11:55:00 methionine adenosyltransferase II alpha (MAT2A), and the arginine methyltransferase, PRMT5, as vulnerable enzymes in cells with MTAP deletion. 27068473
2014-10-18 11:23:00 The RIO kinase fold generates a versatile ATPase enzyme, which in the case of Rio1 is activated following the Rio2 step to regulate one of the final 40S maturation events, at which time the 60S subunit is recruited for final quality control check. 24948609

名称对应

Type IDs
Synonymous AD034, RIO1, RRP10, bA288G3.1
Gene
UniProtKB-ID: RIOK1_HUMAN
UniprotKB: Q9BRS2
UniParc: UPI000003FDCE
EMBL: BC006104, AK314467, CH471087, AK054568, AL834277
Ensembl: ENSG00000124784
KO: hsa:83732
Nucleutide sequences
EMBL-CDS: CAD38952.1, BAB70761.1, EAW55210.1, BAG37075.1, AAH06104.2
Ensembl_TRS: ENST00000379834
Protein sequencees
Ensembl_PRO: ENSP00000369162
RefSeq: NP_001335123.1, XP_011513235.2, NP_113668.2
Others
UniRef100: UniRef100_Q9BRS2
UniRef90: UniRef90_Q9BRS2
UniRef50: UniRef50_Q9BRS2
UniGene: Hs.437474
CCDS: CCDS4500.1

全选

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