| Type | Description |
|---|---|
| Definition | cysteine rich secretory protein LCCL domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 11:33:00 | Our findings suggest that using specific asthma characteristics, such as airway hyperresponsiveness, can help identify more genetically homogeneous asthma subgroups with genotype-phenotype associations that may not be observed in all children with asthma. CRISPLD2 also may be important for baseline lung function in individuals with asthma who also may have airway hyperresponsiveness. | 31557467 |
| 2019-06-08 11:57:00 | CRISPLD2 rs4783099 was associated with cleft lip and/or palate (CL/P) statistically (OR = 3.18, P < .01). Compared to genotype TT, genotypes CC and CT were correlated significantly (OR = 2.04, P = .04) with CL/P. No evidence showed an association between genetic variation at the CRISPLD2 locus and cleft palate only (CP). | 29437515 |
| 2019-03-09 12:59:00 | we demonstrated that knockdown of Crispld2 in zebrafish alters neural crest cell migration patterns resulting in abnormal jaw and palate development. In this study, we performed RNA profiling in zebrafish embryos and identified 249 differentially expressed genes following knockdown of Crispld2. | 29899370 |
| 2018-02-17 11:18:00 | Our results suggest that CRISPLD2 rs4783099 may represent a risk factor for NSCPO (non-syndromic oral clefts). | 27328068 |
| 2017-10-28 12:12:00 | Data suggest that suppression of CRISPLD2 increases the risk of lung inflammation in early life and adulthood. | 27597766 |
| Type | IDs |
|---|---|
| Synonymous | CRISP11, LCRISP2, LGL1 |
| Gene |
UniProtKB-ID:
CRLD2_HUMAN,
A0A140VK80_HUMAN
UniprotKB:
Q9H0B8,
A0A140VK80
UniParc:
UPI00000736BC,
UPI00000411B0,
UPI000006D152,
UPI0000048EF0,
UPI0000DD0935
EMBL:
AY358413,
AK027395,
BC007689,
HM005620,
CH471114,
AL136861,
AY358790,
BC063012
Ensembl:
ENSG00000103196
KO:
hsa:83716
|
| Nucleutide sequences |
EMBL-CDS:
EAW95468.1,
AAH07689.1,
AAQ89150.1,
AAQ88779.1,
AAH63012.1,
BAB55081.1,
CAB66795.1,
EAW95469.1,
AEE61217.1
Gene_ORFName:
UNQ2914/PRO1156/PRO9783
Ensembl_TRS:
ENST00000262424,
ENST00000564567,
ENST00000569090
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000457655,
ENSP00000262424,
ENSP00000454858
RefSeq:
NP_113664.1,
XP_005256247.1,
XP_024306231.1
|
| Others |
UniRef100:
UniRef100_Q9H0B8
UniRef90:
UniRef90_Q9H0B8
UniRef50:
UniRef50_Q9H0B8
UniGene:
Hs.513779,
Hs.617091
CCDS:
CCDS10949.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员