| Type | Description |
|---|---|
| Definition | dynein light chain roadblock-type 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-01-17 12:26:00 | Human colorectal carcinoma cells display decreased tumor progression and invasion when a novel anti-cell motility target, DYNLRB1, is being silenced. | 23755307 |
| 2013-04-27 10:35:00 | TGFbeta regulates km23-1 interaction with the R1beta regulatory subunit of protein kinase A. | 23333499 |
| 2013-03-30 13:09:00 | these findings demonstrate that km23-1 regulates RhoA and motility-associated actin modulating proteins, suggesting that km23-1 may represent a novel target for anti-metastatic therapy. | 23079622 |
| 2012-10-13 11:16:00 | km23-1 is required for TGFbeta1 autoinduction through Smad2-independent Ras/ERK/JNK pathways | 22637579 |
| 2010-01-21 00:00:00 | Findings indicate that km23-2 (DYNLRB2) is required for Smad3-dependent TGFbeta signaling. Km23-2 has functions in TGFbeta signaling that are distinct from those for km23-1 (DYNLRB1). | 19711352 |
| Type | IDs |
|---|---|
| Synonymous | BITH, BLP, DNCL2A, DNLC2A, ROBLD1 |
| Gene |
UniProtKB-ID:
DLRB1_HUMAN,
B4DFR2_HUMAN
UniprotKB:
Q9NP97,
B4DFR2
UniParc:
UPI0000040BFB,
UPI000006F3B8,
UPI00017A6F89
EMBL:
BC002481,
AY026513,
AF165516,
AL109923,
AF178431,
BC007223,
AF161511,
AK294214,
AF132750,
AL136173
Ensembl:
ENSG00000125971
KO:
hsa:83658
|
| Nucleutide sequences |
EMBL-CDS:
AAL75951.1,
AAF86646.1,
AAF29126.1,
AAK95342.1,
AAK18712.1,
AAH02481.1,
BAG57523.1
Gene_ORFName:
HSPC162
Ensembl_TRS:
ENST00000300469,
ENST00000357156
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349679,
ENSP00000300469
RefSeq:
NP_001306086.1,
NP_001369295.1,
NP_001369296.1,
NP_001369294.1,
NP_054902.1
|
| Others |
UniRef100:
UniRef100_B4DFR2,
UniRef100_Q9NP97
UniRef90:
UniRef90_Q9NP97,
UniRef90_B4DFR2
UniRef50:
UniRef50_Q9NP97
UniGene:
Hs.593920
CCDS:
CCDS13235.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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